CENPC

Gene Name		centromere protein C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleus Nucleoplasm Pericentric Heterochromatin Cytoplasm Cytosol
	Molecular Function	DNA Binding Centromeric DNA Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly Chromosome Segregation Mitotic Nuclear Division CENP-A Containing Nucleosome Assembly Cell Division Kinetochore Assembly
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: DAXX MAPK14 MDC1 SUMO2 TCEB1 UBTF
Entrez ID		1060
HPRD ID		00315
Ensembl ID		ENSG00000145241
Uniprot IDs		Q03188 Q6PIR0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Elongation Cellular Response To Stress P38MAPK Cascade Positive Regulation Of Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity DNA Damage Checkpoint Chromatin Remodeling Transcription, DNA-templated Positive Regulation Of MAP Kinase Activity Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration RNA Biosynthetic Process MAPK Cascade Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Brown Fat Cell Differentiation Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Cellular Nitrogen Compound Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Metabolic Process 3'-UTR-mediated MRNA Stabilization Intra-S DNA Damage Checkpoint Positive Regulation Of Transcription From RNA Polymerase I Promoter Stress-induced Premature Senescence Positive Regulation Of Transcription, DNA-templated Cell Cycle Nitrogen Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Response To Muramyl Dipeptide Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase I Promoter Positive Regulation Of MAPK Cascade Positive Regulation Of Erythrocyte Differentiation Response To Stress Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
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