CDK11B

Description		cyclin dependent kinase 11B
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GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of DNA-templated Transcription Protein Phosphorylation Apoptotic Process Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of MRNA Processing Regulation Of Cell Cycle
Pathways		Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Novel Interacting Genes		1 novel interacting genes: PPIL3
Interacting Genes		26 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F H1-1 KAT7 MSN PAK1 PDE4B PIN1 RANBP9 RNF10 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID		984
HPRD ID		08909
Ensembl ID		ENSG00000248333
Uniprot IDs		B4DII1 P21127
PDB IDs		7UKZ
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Targeting Protein Sequestering Activity Cytosol Nucleus Transmembrane Transporter Binding Focal Adhesion Regulation Of Protein Localization Vesicle Protein Modification Process Cytoplasm Protein Domain Specific Binding Enzyme Binding Post-translational Protein Modification Phosphoprotein Binding Identical Protein Binding Response To Anesthetic Regulation Of Primary Metabolic Process Pyroptotic Inflammatory Response Regulation Of Macromolecule Metabolic Process Cysteine-type Peptidase Activity Death-inducing Signaling Complex Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Immune System Process Positive Regulation Of Pyroptotic Inflammatory Response Ubiquitin Protein Ligase Binding Regulation Of Protein Localization To Nucleus Response To Cobalt Ion Cysteine-type Endopeptidase Activity Negative Regulation Of Intracellular Signal Transduction Regulation Of Metabolic Process Protein Metabolic Process Regulation Of System Process Negative Regulation Of Signal Transduction Interleukin-18-mediated Signaling Pathway Intracellular Signal Transduction Protein Tag Activity Regulation Of Protein Stability Protein Catabolic Process Immune System Process Proteolysis Death Receptor Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Poly-ADP-ribosylation Response To Starvation Positive Regulation Of Myelination Cellular Response To Stress Regulation Of Gene Expression Microtubule Polymerization
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