KLF5 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 21953463)
  • 6
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

KLF5

SMURF2

Gene Name Kruppel-like factor 5 (intestinal) SMAD specific E3 ubiquitin protein ligase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 18 interactors: CREBBP EP300 ESR1 FBXW7 GSK3B GTF2B GTF2E2 GTF2F1 GTF2F2 HDAC1 NFKB1 PRKCA PRKCD RARA SET SMURF2 TBP WWP1 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 688 64750
HPRD ID 04212 06901
Ensembl ID ENSG00000102554
Uniprot IDs A2TJX0 Q13887 Q5T6X2 Q96DE7 Q9HAU4
PDB IDs 2EBT 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
3t3  activities  adipocyte  adipocytes  adipogenesis  adipogenic  ampk  ap2  atorvastatin  attractive  cascades  combination  diseases  ebpalpha  elevated  excessive  exerts  homeostasis  l1  master  metformin  obesity  ppargamma  regulator  regulators  smad7  stat3  suppressed  tgf 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
3t3  activities  adipocyte  adipocytes  adipogenesis  adipogenic  ampk  ap2  atorvastatin  attractive  cascades  combination  diseases  ebpalpha  elevated  excessive  exerts  homeostasis  l1  master  metformin  obesity  ppargamma  regulator  smad7  stat3  suppressed  tgf 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?
regulators