TADA2A and PRPF31

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TADA2A	PRPF31
Gene Name		transcriptional adaptor 2A	pre-mRNA processing factor 31
Image
Gene Ontology Annotations	Cellular Component	PCAF Complex Nucleus Chromosome	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Histone Acetyltransferase Activity Zinc Ion Binding	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Histone H3 Acetylation	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		34 interactors: ARNT2 C1orf109 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FAM127C FARS2 FBF1 GPSM3 HGS KAT2A KLC4 KLHL38 KPNA2 LOC149950 MAGOH MCPH1 MFAP1 MTX2 MYC NR3C1 PPP1R16B PRKAB2 PRPF31 SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564	55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587
Entrez ID		6871	26121
HPRD ID		03784	05917
Ensembl ID		ENSG00000108264	ENSG00000105618
Uniprot IDs		O75478	E7ESA8 F1T0A4 F1T0A5 Q8WWY3
PDB IDs		1X41	2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		Histone H3 Acetylation Gene Expression RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Histone Acetylation Heterocycle Metabolic Process Internal Peptidyl-lysine Acetylation Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Chromatin Modification Transcription, DNA-templated Cytoplasmic Transport RNA Biosynthetic Process Chromatin Organization Regulation Of Gluconeogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Glucocorticoid Mediated Signaling Pathway Exocyst Assembly Cellular Macromolecule Biosynthetic Process Establishment Of Localization In Cell Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Histone H4 Acetylation Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Organelle Organization Positive Regulation Of Cell Proliferation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Peptidyl-serine Dephosphorylation Fibroblast Apoptotic Process Protein Localization To Organelle Transcription From RNA Polymerase II Promoter Peptidyl-lysine Modification Intracellular Steroid Hormone Receptor Signaling Pathway Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Chromosome Condensation Regulation Of Metabolic Process Cellular Protein Localization Cellular Localization	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly
Tagcloud ?			ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Difference) ?			ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Intersection) ?