TADA2A and TADA3

Number of citations of the paper that reports this interaction (PubMedID 11707411)
47

Data Source:
HPRD (two hybrid, in vitro)

		TADA2A	TADA3
Description		transcriptional adaptor 2A	transcriptional adaptor 3
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Chromosome SAGA-type Complex Mitotic Spindle ATAC Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFTC Complex Mitotic Spindle ATAC Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding
	Biological Process	Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Estrogen Receptor Signaling Pathway Regulation Of Protein Stability Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	HATs acetylate histones Ub-specific processing proteases Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: AIRIM ARNT2 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688	35 interacting genes: ADPGK ANKRD12 ANKRD36B AR CCNC CEBPA CENPB EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 OGT PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 STX11 TADA2A TP53 TXLNB TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		6871	10474
HPRD ID		03784	04252
Ensembl ID		ENSG00000276234	ENSG00000171148
Uniprot IDs		A0A024R0Y4 A0A087WWR4 A0A0S2Z4G1 B3KU13 O75478	A0A024R2D7 A8K899 O75528
PDB IDs		1X41
Enriched GO Terms of Interacting Partners?		Protein Binding U2-type Precatalytic Spliceosome Nuclear Speck Exon-exon Junction Subcomplex Mago-y14 Nucleus U2-type Spliceosomal Complex Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Stress-activated MAPK Cascade Membrane Fission RNA Splicing, Via Transesterification Reactions Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Cytoplasm Centrosome Nuclear Export RNA Splicing ATAC Complex Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Nuclear Receptor Activity Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of RNA Metabolic Process Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Coactivator Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Steroid Receptor Activity Retinoic Acid-responsive Element Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Chromatin Transcription Cis-regulatory Region Binding Chromatin DNA Binding DNA Binding Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Nucleus DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Sequence-specific DNA Binding Cellular Response To Estrogen Stimulus DNA-binding Transcription Factor Activity Intracellular Receptor Signaling Pathway MRNA Transcription Response To Estrogen Regulation Of Macromolecule Metabolic Process Hormone-mediated Signaling Pathway Enzyme Binding Positive Regulation Of Macromolecule Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Histone Acetyltransferase Complex Protein-containing Complex Regulation Of MiRNA Transcription
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