TADA2A and KLC4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TADA2A	KLC4
Description		transcriptional adaptor 2A	kinesin light chain 4
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Chromosome SAGA-type Complex Mitotic Spindle ATAC Complex	Cytoplasm Cytoskeleton Kinesin Complex Microtubule
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Kinesin Binding
	Biological Process	Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle	Microtubule-based Movement
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)	Hemoglobin levels ( 32327693)
Interacting Genes		49 interacting genes: AIRIM ARNT2 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688	32 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 KATNAL1 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A TSC1 USHBP1 YWHAE YWHAZ ZNF343
Entrez ID		6871	89953
HPRD ID		03784	13932
Ensembl ID		ENSG00000276234	ENSG00000137171
Uniprot IDs		A0A024R0Y4 A0A087WWR4 A0A0S2Z4G1 B3KU13 O75478	Q9NSK0
PDB IDs		1X41
Enriched GO Terms of Interacting Partners?		Protein Binding U2-type Precatalytic Spliceosome Nuclear Speck Exon-exon Junction Subcomplex Mago-y14 Nucleus U2-type Spliceosomal Complex Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Stress-activated MAPK Cascade Membrane Fission RNA Splicing, Via Transesterification Reactions Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Cytoplasm Centrosome Nuclear Export RNA Splicing ATAC Complex Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Cytoskeleton Organization Intermediate Filament Cytoskeleton Keratin Filament Organelle Organization Structural Molecule Activity Tissue Morphogenesis Microtubule-based Process Morphogenesis Of An Epithelium Anatomical Structure Morphogenesis Phosphoserine Residue Binding Identical Protein Binding Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell Differentiation Cardiac Conduction Microtubule Binding Transmembrane Transporter Binding Epidermis Development Neuron Migration Microtubule Cytoskeleton Organization Centrosome Cytoplasmic Microtubule Organization Hair Cycle Protein Binding Molecular Adaptor Activity Microtubule Regulation Of Golgi Organization Microtubule Organizing Center Organization Developmental Process Microtubule Organizing Center Structural Constituent Of Cytoskeleton Regulation Of Heart Rate Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Blood Circulation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Cytosol Concave Side Of Sperm Head Maintenance Of Protein Localization At Cell Tip Memory T Cell Differentiation Positive Regulation Of Microtubule Polymerization
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