TACR3 and GPRASP1

Number of citations of the paper that reports this interaction (PubMedID 15452121)
0

Data Source:
HPRD (in vitro)

		TACR3	GPRASP1
Description		tachykinin receptor 3	G protein-coupled receptor associated sorting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Membrane Neuronal Cell Body Membrane Sperm Midpiece	Nucleus Cytoplasm Cytosol
	Molecular Function	G Protein-coupled Receptor Activity Tachykinin Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Osanetant Talnetant Pavinetant
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Chronotype ( 30696823) Heel bone mineral density ( 30598549) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Menarche (age at onset) ( 25231870 27182965) Rosacea symptom severity ( 29771307) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		4 interacting genes: GPRASP1 TAC1 TAC3 TAC4	48 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 DSCAM F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		6870	9737
HPRD ID		01209	02333
Ensembl ID		ENSG00000169836	ENSG00000198932
Uniprot IDs		P29371	Q5JY77
PDB IDs		8JBF 8JBG 8JBH
Enriched GO Terms of Interacting Partners?		Substance K Receptor Binding Tachykinin Receptor Signaling Pathway Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Cilium Movement Regulation Of Flagellated Sperm Motility Substance P Receptor Binding Neuromedin K Receptor Binding Regulation Of Cilium Movement Regulation Of Microtubule-based Movement Positive Regulation Of Sensory Perception Of Pain Positive Regulation Of Reproductive Process Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Regulation Of Blood Pressure Regulation Of Sensory Perception Of Pain Regulation Of Reproductive Process Detection Of Temperature Stimulus Involved In Sensory Perception Negative Regulation Of Systemic Arterial Blood Pressure Detection Of Temperature Stimulus Regulation Of Microtubule-based Process Negative Regulation Of Blood Pressure Neuropeptide Signaling Pathway Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Nervous System Process Detection Of Abiotic Stimulus Receptor Ligand Activity G Protein-coupled Receptor Catabolic Process Detection Of Stimulus Involved In Sensory Perception Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Temperature Stimulus G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Corticosterone Secretion Negative Regulation Of Sensory Perception Of Pain Insemination Regulation Of Corticosterone Secretion Regulation Of Cell Motility Positive Regulation Of Synaptic Transmission, Cholinergic Detection Of Stimulus Regulation Of Locomotion Positive Regulation Of Action Potential Antifungal Humoral Response Negative Regulation Of Heart Rate Response To Yeast Positive Regulation Of Synaptic Transmission, GABAergic Response To Pain Extracellular Space Receptor Catabolic Process Negative Regulation Of Nervous System Process Negative Regulation Of Heart Contraction Neuronal Dense Core Vesicle	G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G Protein-coupled Acetylcholine Receptor Activity Regulation Of Blood Pressure Signal Transduction Regulation Of Smooth Muscle Contraction Trans-synaptic Signaling System Process Synaptic Signaling G Protein-coupled Peptide Receptor Activity Regulation Of System Process G Protein-coupled Acetylcholine Receptor Signaling Pathway Postsynaptic Membrane Chemical Synaptic Transmission Vascular Process In Circulatory System Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Blood Pressure Dendrite Blood Vessel Diameter Maintenance Regulation Of Tube Size Circulatory System Process G Protein-coupled Opioid Receptor Activity Acetylcholine Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Postsynaptic Signal Transduction Positive Regulation Of Muscle Contraction Plasma Membrane G Protein-coupled Opioid Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Smooth Muscle Contraction Signaling Regulation Of Biological Quality Positive Regulation Of Flagellated Sperm Motility Tachykinin Receptor Activity Cell Communication Regulation Of Muscle Contraction Positive Regulation Of Cilium Movement Regulation Of Blood Circulation Regulation Of Flagellated Sperm Motility Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Muscle System Process Positive Regulation Of MAPK Cascade
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