VAMP2 and STX1B

Number of citations of the paper that reports this interaction (PMID 12093152)
3

Data Source:
BioGRID (two hybrid)

		VAMP2	STX1B
Gene Name		vesicle-associated membrane protein 2 (synaptobrevin 2)	syntaxin 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Cytosol Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Secretory Granule Membrane Synaptic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Zymogen Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Vesicular Exosome Clathrin-sculpted Monoamine Transport Vesicle Membrane	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane SNARE Complex
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Syntaxin Binding Protein Self-association Calcium-dependent Protein Binding	SNARE Binding SNAP Receptor Activity Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Energy Reserve Metabolic Process Protein Complex Assembly Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Fusion Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Glucose Glutamate Secretion Protein Transport Synaptic Vesicle Exocytosis Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Regulation Of Exocytosis Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Cellular Protein Metabolic Process Small Molecule Metabolic Process Regulation Of Insulin Secretion Long-term Synaptic Potentiation Regulation Of Vesicle-mediated Transport Membrane Organization Membrane Fusion Mucus Secretion Positive Regulation Of Intracellular Protein Transport Regulation Of Histamine Secretion By Mast Cell	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Pathogenesis Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways		Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Toxicity of botulinum toxin type D (BoNT/D) Golgi Associated Vesicle Biogenesis Translocation of GLUT4 to the plasma membrane GABA synthesis, release, reuptake and degradation Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins trans-Golgi Network Vesicle Budding Toxicity of botulinum toxin type G (BoNT/G) Regulation of insulin secretion Norepinephrine Neurotransmitter Release Cycle Toxicity of tetanus toxin (TeNT) Toxicity of botulinum toxin type F (BoNT/F) Glutamate Neurotransmitter Release Cycle Toxicity of botulinum toxin type B (BoNT/B) Insulin processing Transmission across Chemical Synapses	Uptake and actions of bacterial toxins Toxicity of botulinum toxin type C (BoNT/C) Neurotoxicity of clostridium toxins
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ASNA1 ATP13A2 BAG6 BCAP31 CPLX1 FKBP2 PRKD3 RABAC1 SNAP23 SNAP25 SNAP29 STX11 STX1A STX1B STX2 STX3 STX4 STXBP2 STXBP3 SYP SYPL1 TRPC3 VAMP3 VAMP8 VAPA VAPB	5 interactors: SNAP23 STXBP1 UNC13B VAMP1 VAMP2
Entrez ID		6844	112755
HPRD ID		01717	18126
Ensembl ID		ENSG00000220205	ENSG00000099365
Uniprot IDs		F8WCA0 P63027	P61266
PDB IDs		3FIE 3FII 3RK2 3RK3 3RL0
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Vesicle Organization Organelle Fusion Membrane Fusion Synaptic Vesicle Exocytosis Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Vesicle Docking Membrane Organization Membrane Docking Regulation Of Neurotransmitter Levels Neurotransmitter Transport Secretion By Cell Vesicle-mediated Transport Establishment Of Vesicle Localization Vesicle Localization Secretion Cellular Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Cell-cell Signaling Transport Establishment Of Protein Localization Protein Localization Organelle Localization Synaptic Transmission Protein Transport Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Cell Communication Regulation Of Cellular Localization Signaling Organelle Organization Golgi Vesicle Transport Regulation Of Secretion Intracellular Transport Neutrophil Degranulation Cellular Protein Localization Synaptic Vesicle Docking SNARE Complex Assembly Regulation Of Vesicle-mediated Transport Neutrophil Activation Involved In Immune Response Synaptic Vesicle Priming Positive Regulation Of Synaptic Transmission Leukocyte Degranulation Regulated Secretory Pathway Regulation Of Synaptic Transmission Negative Regulation By Host Of Viral Genome Replication	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Secretion By Cell Regulation Of Neurotransmitter Levels Glutamate Secretion Neurotransmitter Transport Secretion Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle Fusion Synaptic Vesicle Exocytosis Acid Secretion Establishment Of Organelle Localization Organelle Fusion Dicarboxylic Acid Transport Organelle Localization Vesicle-mediated Transport Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Membrane Fusion Synaptic Transmission Regulation Of Exocytosis Amino Acid Transport Anion Transport Regulation Of Synaptic Plasticity Establishment Of Localization In Cell Membrane Organization Cell-cell Signaling Cellular Localization Protein Complex Assembly Regulation Of Synaptic Vesicle Exocytosis Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Regulation Of Synaptic Vesicle Transport Cellular Protein Complex Assembly Leukocyte Degranulation Regulation Of Vesicle-mediated Transport Regulated Secretory Pathway Organic Anion Transport Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Neurotransmitter Secretion Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Ion Transport Cellular Macromolecular Complex Assembly
Tagcloud ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp1
Tagcloud (Difference) ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp1
Tagcloud (Intersection) ?