SUPT4H1 and PDLIM1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SUPT4H1	PDLIM1
Gene Name		suppressor of Ty 4 homolog 1 (S. cerevisiae)	PDZ and LIM domain 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DSIF Complex	Transcription Factor Complex Cytoplasm Cytoskeleton Focal Adhesion
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Heterodimerization Activity	Transcription Coactivator Activity Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	Response To Hypoxia Regulation Of Transcription, DNA-templated Response To Oxidative Stress
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ANXA5 APP EWSR1 HMP19 HTATSF1 LRIF1 PDLIM1 SUPT5H XRCC5	13 interactors: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		6827	9124
HPRD ID		16026	09326
Ensembl ID		ENSG00000213246	ENSG00000107438
Uniprot IDs		P63272	O00151
PDB IDs		3H7H	1X62 2PKT
Enriched GO Terms of Interacting Partners?		Viral Genome Replication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of DNA-templated Transcription, Elongation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Hyperosmotic Salinity Response Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Transcription, DNA-templated RNA Biosynthetic Process Viral Process Collateral Sprouting In Absence Of Injury Cellular Response To X-ray Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cellular Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Viral Life Cycle Nucleobase-containing Compound Metabolic Process Axon Choice Point Recognition Establishment Of Integrated Proviral Latency Heterocycle Metabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Cellular Aromatic Compound Metabolic Process Neuron Remodeling Establishment Of Viral Latency Cellular Nitrogen Compound Metabolic Process Cellular Response To Salt Stress Hematopoietic Stem Cell Differentiation Positive Regulation Of Macroautophagy Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Response To Abiotic Stimulus Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Negative Regulation Of DNA-templated Transcription, Elongation Double-strand Break Repair Via Nonhomologous End Joining Hyperosmotic Response Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Blood Coagulation Response To Oxidative Stress	Protein Localization To Tight Junction Bergmann Glial Cell Differentiation Protein Localization To Cell Junction Platelet Degranulation Intermediate Filament Organization Actin Crosslink Formation Astrocyte Development Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Actin Filament-based Process Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Response To Wounding Positive Regulation Of Transporter Activity Actin Filament Bundle Assembly Actin Filament-based Movement Histone H2A-S1 Phosphorylation Subthalamic Nucleus Development Prolactin Secreting Cell Differentiation Random Inactivation Of X Chromosome Positive Regulation Of Schwann Cell Proliferation Superior Vena Cava Morphogenesis Apical Junction Assembly Exocytosis Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Cell Proliferation Involved In Outflow Tract Morphogenesis Subthalamus Development Left Lung Morphogenesis Pulmonary Vein Morphogenesis Blood Coagulation Glial Cell Development Hemostasis Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Extraocular Skeletal Muscle Development Pulmonary Myocardium Development Positive Regulation Of Pinocytosis Left Lung Development Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development
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