SUPT4H1 and HTATSF1

Number of citations of the paper that reports this interaction (PMID 10454543)
18

Data Source:
HPRD (in vivo)

		SUPT4H1	HTATSF1
Gene Name		suppressor of Ty 4 homolog 1 (S. cerevisiae)	HIV-1 Tat specific factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DSIF Complex	Nucleus Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Heterodimerization Activity	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Genome Replication Regulation Of DNA-templated Transcription, Elongation
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ANXA5 APP EWSR1 HMP19 HTATSF1 LRIF1 PDLIM1 SUPT5H XRCC5	15 interactors: APBB1 CCNT1 CDK9 CSNK2A1 FEZ1 GTF2F2 POLR2A SF3A2 SNRNP70 SNRPB2 SRSF4 SUPT4H1 SUPT5H WBP4 ZNF512B
Entrez ID		6827	27336
HPRD ID		16026	02282
Ensembl ID		ENSG00000213246	ENSG00000102241
Uniprot IDs		P63272	O43719
PDB IDs		3H7H	2DIT
Enriched GO Terms of Interacting Partners?		Viral Genome Replication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of DNA-templated Transcription, Elongation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Hyperosmotic Salinity Response Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Transcription, DNA-templated RNA Biosynthetic Process Viral Process Collateral Sprouting In Absence Of Injury Cellular Response To X-ray Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cellular Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Viral Life Cycle Nucleobase-containing Compound Metabolic Process Axon Choice Point Recognition Establishment Of Integrated Proviral Latency Heterocycle Metabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Cellular Aromatic Compound Metabolic Process Neuron Remodeling Establishment Of Viral Latency Cellular Nitrogen Compound Metabolic Process Cellular Response To Salt Stress Hematopoietic Stem Cell Differentiation Positive Regulation Of Macroautophagy Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Response To Abiotic Stimulus Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Negative Regulation Of DNA-templated Transcription, Elongation Double-strand Break Repair Via Nonhomologous End Joining Hyperosmotic Response Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Blood Coagulation Response To Oxidative Stress	RNA Metabolic Process Positive Regulation Of Viral Transcription Gene Expression Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of Viral Process Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing RNA Splicing Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process 7-methylguanosine MRNA Capping Positive Regulation Of Gene Expression 7-methylguanosine RNA Capping Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process DNA-templated Transcription, Initiation Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Splicing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Metabolic Process Positive Regulation Of RNA Splicing Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of DNA-templated Transcription, Elongation
Tagcloud ?			18s actb ap3d1 bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?			18s actb ap3d1 bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?