Wiki-Pi
About
Search
People
Updates
Search
TERF1 and EPB41L1
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TERF1
EPB41L1
Description
telomeric repeat binding factor 1
erythrocyte membrane protein band 4.1 like 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Fibrillar Center
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Spindle
Cytoskeleton
Nuclear Body
Shelterin Complex
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Molecular Function
DNA Binding
Double-stranded Telomeric DNA Binding
Telomerase Activity
Protein Binding
Microtubule Binding
DNA Binding, Bending
Telomeric DNA Binding
Identical Protein Binding
Protein Homodimerization Activity
Ankyrin Repeat Binding
G-rich Strand Telomeric DNA Binding
Actin Binding
Structural Molecule Activity
Protein Binding
Cytoskeletal Protein Binding
Biological Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Response To Xenobiotic Stimulus
Telomere Capping
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Meiotic Telomere Clustering
Cell Division
Telomeric D-loop Disassembly
T-circle Formation
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Shelterin Complex Assembly
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Telomeric D-loop Disassembly
Cortical Actin Cytoskeleton Organization
Actomyosin Structure Organization
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Trafficking of AMPA receptors
Neurexins and neuroligins
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS
Age at first sexual intercourse (
34211149
)
Crohn's disease (
22412388
)
Leukocyte telomere length (
31171785
)
Telomere length (
33941849
)
Basal cell carcinoma (
33549134
)
Height (
23563607
)
Hip circumference (
25673412
)
Hip circumference adjusted for BMI (
34021172
)
Keratinocyte cancer (MTAG) (
31174203
)
Refractive error (
32231278
)
Waist circumference adjusted for body mass index (
34021172
)
Interacting Genes
212 interacting genes:
ACAT2
ACOT7
ACY1
AFAP1L2
AHCY
AK1
AKR1A1
ALDOA
AMPD2
AMPH
ANXA2
ANXA5
ANXA8L1
APEX1
ARHGDIA
ARHGEF3
ARPP21
ASS1
ATM
BCL7B
BIN2
BLM
BRAF
C12orf43
C1orf35
CALD1
CAPNS1
CASP7
CCDC9
CDC6
CDK1
CEP85
CFL1
CKB
CORO1B
CPNE3
CRYBB1
CRYM
DBN1
DBNL
DCX
DDX19B
DDX21
DDX23
DDX24
DDX39A
DLG5
DNAAF11
DNAJB1
DNPH1
DPP3
DPYSL3
EEF1D
EIF4B
ENO2
EPB41L1
EPHX2
EVL
FANCD2
FBP1
FBXO4
FEN1
FES
FKBP8
GAMT
GAPDH
GIT1
GNL3L
GNMT
GSS
H1-1
HCLS1
HDGFL2
HEXIM1
HEXIM2
HGD
HMGN3
HMGN4
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA6
IPO5
JSRP1
KCTD7
KDM1A
KEAP1
KIFBP
KLHDC4
KPNB1
LASP1
LDHA
LDHB
LRSAM1
LYAR
MAP4
MAP7
MAPK12
MAPRE1
MCM2
MDH1
MISP
MSN
MT1X
MVK
NAP1L1
NBN
NEFL
NEK7
NME1
NME2
NOL12
NOL3
NRIP1
NUDCD2
NUDT14
NUMA1
NXNL1
OCM2
OGFR
OGT
PA2G4
PACSIN2
PAFAH1B3
PAGE2
PAICS
PAK4
PCLAF
PCP4
PEPD
PFKP
PFN2
PGD
PGLS
PGM1
PGM2
PINX1
PKM
PNMT
POT1
PPM1G
PRDX1
PRDX6
PRKCB
PTMA
PTPN5
RBMY1A1
RECQL4
RIC8A
RLIM
RNF10
RPAP3
RPL19
RTN3
RTN4
SALL1
SARS1
SBDS
SENP8
SET
SH3BP1
SH3GL2
SH3GL3
SHFL
SIRPD
SKP1
SMAD9
SMARCC2
SNCG
SOAT1
SP100
SRM
SRSF6
STUB1
SULT1C2
SUPT5H
SYK
TALDO1
TBC1D10A
TBCD
TBL1X
TCIRG1
TERT
THG1L
TINAG
TINF2
TKT
TMSB10
TMSB4Y
TNKS
TNKS2
TNPO2
TOMM34
TPI1
TRIM16
TRIP10
TRMT1
TUBB2A
TUBB3
TUBB4B
UBE2M
UTP14A
WARS1
WDR4
WFS1
YWHAG
ZBTB16
ZC3H18
ZFP36L1
ZHX1
ZNF790
20 interacting genes:
AGAP2
APP
ARHGAP1
CHRM5
DRD2
DRD3
GRIA1
GRIA4
HSPB1
ITPR1
NR3C1
NUMA1
POT1
SRPK2
STARD13
TERF1
USP40
YWHAB
YWHAQ
YWHAZ
Entrez ID
7013
2036
HPRD ID
02975
04193
Ensembl ID
ENSG00000147601
ENSG00000088367
Uniprot IDs
A0A7I2V5T5
A0A7I2YQE7
P54274
A0A0C4DH22
B7Z653
Q9H4G0
PDB IDs
1BA5
1H6O
1ITY
1IV6
1W0T
3BQO
3L82
5HKP
5WIR
5XUP
8F0A
8F0U
8F1T
8F1U
8F21
8F26
8OX1
8W8G
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Extracellular Exosome
Identical Protein Binding
Protein Binding
Nucleobase-containing Compound Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Telomere Maintenance
Chromosome, Telomeric Region
Nucleobase-containing Small Molecule Metabolic Process
Purine-containing Compound Metabolic Process
Telomere Organization
Cadherin Binding
Nucleus
Negative Regulation Of Telomere Maintenance
Purine Nucleotide Metabolic Process
ADP Metabolic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Chromosome Organization
Positive Regulation Of Chromosome Organization
Nucleoside Diphosphate Metabolic Process
Glycolytic Process
Pyruvate Metabolic Process
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
ADP Catabolic Process
Nucleotide Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Phosphate Metabolic Process
Ficolin-1-rich Granule Lumen
Nucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Nucleoside Phosphate Catabolic Process
RNA Binding
Phosphate-containing Compound Metabolic Process
Microtubule Cytoskeleton Organization
Negative Regulation Of DNA Metabolic Process
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Purine Nucleotide Catabolic Process
Protein Localization To Organelle
Positive Regulation Of Protein-containing Complex Assembly
Cytoskeleton
Positive Regulation Of Organelle Organization
Organelle Organization
Catalytic Activity
Small Molecule Metabolic Process
Organophosphate Catabolic Process
Trans-synaptic Signaling
Chemical Synaptic Transmission
Synaptic Signaling
Ligand-gated Ion Channel Signaling Pathway
Protein Domain Specific Binding
Synapse
Response To Morphine
Regulation Of Neurotransmitter Uptake
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Associative Learning
Intracellular Signaling Cassette
Negative Regulation Of Protein Localization
Regulation Of Protein Localization
Signal Transduction
Acid Secretion
Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go
Signaling
Ionotropic Glutamate Receptor Signaling Pathway
Cell Communication
Intracellular Signal Transduction
Dendrite
Negative Regulation Of Synaptic Transmission
Dopamine Neurotransmitter Receptor Activity
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Protein-containing Complex
Response To Cocaine
Positive Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Establishment Of Protein Localization
Regulation Of Locomotion Involved In Locomotory Behavior
AMPA Glutamate Receptor Activity
Synaptic Transmission, Glutamatergic
Shelterin Complex
Phosphoserine Residue Binding
Negative Regulation Of Protein Localization To Nucleus
Regulation Of Establishment Of Protein Localization
Dendritic Spine
Glutamate Receptor Signaling Pathway
Regulation Of G Protein-coupled Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Cycle
Regulation Of Transport
Visual Learning
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission, Glutamatergic
Nuclear Telomere Cap Complex
Telomeric D-loop Disassembly
Visual Behavior
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?