GEMIN5 and STXBP3

Number of citations of the paper that reports this interaction (PMID 12065586)
31

Data Source:
HPRD (in vivo)

		GEMIN5	STXBP3
Gene Name		gem (nuclear organelle) associated protein 5	syntaxin binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Extracellular Vesicular Exosome Tertiary Granule
	Molecular Function	Protein Binding SnRNA Binding Poly(A) RNA Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Protein Complex Assembly Gene Expression NcRNA Metabolic Process	Vesicle Docking Involved In Exocytosis Brain Development Blood Coagulation Protein Transport Glucose Transport Protein To Membrane Docking Insulin Secretion Platelet Activation Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Heterooligomerization Membrane Organization Platelet Aggregation
Pathways		snRNP Assembly Metabolism of non-coding RNA	Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS			Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		19 interactors: DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3	14 interactors: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2
Entrez ID		25929	6814
HPRD ID		06109	10517
Ensembl ID		ENSG00000082516	ENSG00000116266
Uniprot IDs		B7ZLC9 Q58EZ8 Q8TEQ6	O00186
PDB IDs
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Ribonucleoprotein Complex Biogenesis RNA Splicing MRNA Metabolic Process RNA Processing NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Histone MRNA Metabolic Process Spliceosomal Complex Assembly MRNA 3'-end Processing Termination Of RNA Polymerase II Transcription RNA 3'-end Processing Cellular Component Assembly DNA-templated Transcription, Termination RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process JNK Cascade Cellular Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Cellular Response To Reactive Nitrogen Species Transcription From RNA Polymerase II Promoter Activation Of JUN Kinase Activity Programmed Necrotic Cell Death MAPK Cascade Necrotic Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Cell Death Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Response To Hydrogen Peroxide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Signal Transduction By Phosphorylation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway	Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing NcRNA Metabolic Process Cellular Component Assembly RNA Processing Gene Expression Spliceosomal Complex Assembly RNA Metabolic Process Histone MRNA Metabolic Process Regulation Of Exocytosis Regulation Of Insulin Secretion Termination Of RNA Polymerase II Transcription Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Leukocyte Degranulation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Long-term Synaptic Potentiation Regulation Of Secretion Vesicle Fusion Regulation Of Hormone Secretion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Cell Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis DNA-templated Transcription, Termination Exocytosis Vesicle Docking Organelle Fusion MRNA 3'-end Processing Membrane Docking Nitrogen Compound Metabolic Process Positive Regulation Of Eosinophil Degranulation Histone H3-T6 Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Organization Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion RNA 3'-end Processing Eosinophil Degranulation Neurotransmitter Secretion
Tagcloud ?			agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?			agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?