GEMIN5 and RNU2-1

Number of citations of the paper that reports this interaction (PubMedID 23221635)
111

Data Source:
BioGRID (unspecified method)

		GEMIN5	RNU2-1
Description		gem nuclear organelle associated protein 5	RNA, U2 small nuclear 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies	U2 SnRNP
	Molecular Function	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding	Pre-mRNA Branch Point Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Translation Regulation Of Translation RNA Splicing Protein-containing Complex Assembly	MRNA Branch Site Recognition
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Venous thromboembolism ( 32232851)
Interacting Genes		22 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNF10 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2	10 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 SND1 STRAP
Entrez ID		25929	6066
HPRD ID		06109
Ensembl ID		ENSG00000082516	ENSG00000274585
Uniprot IDs		B7ZLC9 Q58EZ8 Q8TEQ6
PDB IDs		5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS 7XDT 7XGR
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Spliceosomal Complex Assembly U2 SnRNP Protein-RNA Complex Assembly U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Methylation Catalytic Step 2 Spliceosome Precatalytic Spliceosome Spliceosomal Complex Protein-containing Complex Assembly Macromolecule Methylation MRNA Metabolic Process Protein-containing Complex Organization SMN Complex Gemini Of Cajal Bodies RNA Modification RNA Processing MRNA Splicing, Via Spliceosome Methylation Spliceosomal Tri-snRNP Complex Cellular Component Assembly Ribonucleoprotein Complex RNA Metabolic Process Telomerase Holoenzyme Complex Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear Body Histone Pre-mRNA DCP Binding RNA Binding Commitment Complex U1 SnRNP Binding JNK Cascade Cytosol	SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing Nuclear Body Nucleic Acid Metabolic Process Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions Protein-containing Complex Organization Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Cytosol Nucleus RNA Binding Cytoplasm Nucleoplasm SMN-Gemin2 Complex RNAi Effector Complex Sm-like Protein Family Complex Cajal Body U2 SnRNP Binding U4atac SnRNA Binding RISC Complex Binding Dense Body U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding MiRNA Catabolic Process Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination
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