GEMIN5 and SNRPD2

Number of citations of the paper that reports this interaction (PubMedID 11714716)
0

Data Source:
HPRD (in vitro)

		GEMIN5	SNRPD2
Description		gem nuclear organelle associated protein 5	small nuclear ribonucleoprotein D2 polypeptide
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal SnRNP Complex Ribonucleoprotein Complex
	Molecular Function	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Translation Regulation Of Translation RNA Splicing Protein-containing Complex Assembly	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery
Drugs			Artenimol
Diseases
GWAS		Venous thromboembolism ( 32232851)	Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Fruit consumption ( 32066663) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		22 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNF10 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2	28 interacting genes: CEBPA CEP70 CINP DDX20 DMTN EEF1G EGFR FOXP1 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF SPANXN2 STRAP STXBP2 STXBP3 WDR77 ZCCHC10
Entrez ID		25929	6633
HPRD ID		06109	03038
Ensembl ID		ENSG00000082516	ENSG00000125743
Uniprot IDs		B7ZLC9 Q58EZ8 Q8TEQ6	K7ERG4 P62316
PDB IDs		5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS 7XDT 7XGR	1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Spliceosomal Complex Assembly U2 SnRNP Protein-RNA Complex Assembly U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Methylation Catalytic Step 2 Spliceosome Precatalytic Spliceosome Spliceosomal Complex Protein-containing Complex Assembly Macromolecule Methylation MRNA Metabolic Process Protein-containing Complex Organization SMN Complex Gemini Of Cajal Bodies RNA Modification RNA Processing MRNA Splicing, Via Spliceosome Methylation Spliceosomal Tri-snRNP Complex Cellular Component Assembly Ribonucleoprotein Complex RNA Metabolic Process Telomerase Holoenzyme Complex Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear Body Histone Pre-mRNA DCP Binding RNA Binding Commitment Complex U1 SnRNP Binding JNK Cascade Cytosol	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Protein-RNA Complex Assembly RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process Spliceosomal Complex Assembly RNA Processing MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly RNA Metabolic Process Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Organization Nucleic Acid Metabolic Process Nuclear Body Cytosol Cellular Component Assembly Nucleobase-containing Compound Metabolic Process U4/U6 X U5 Tri-snRNP Complex Methylosome Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleoplasm Tertiary Granule Spliceosomal Complex Presynaptic Dense Core Vesicle Exocytosis PICln-Sm Protein Complex Neuronal Dense Core Vesicle Exocytosis Neutrophil Degranulation Lsm2-8 Complex 7-methylguanosine Cap Hypermethylation Dense Core Granule Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter U6 SnRNP Nucleus RNA Binding U4 SnRNP Cajal Body Specific Granule Syntaxin-1 Binding Spliceosomal Tri-snRNP Complex Assembly Catalytic Step 2 Spliceosome DNA-templated Transcription Termination Precatalytic Spliceosome U1 SnRNP U5 SnRNP Secretory Granule Localization
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