STRN and TFIP11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		STRN	TFIP11
Description		striatin	tuftelin interacting protein 11
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Bicellular Tight Junction Postsynaptic Density Membrane Cell Junction Dendrite Cell Projection Neuronal Cell Body Dendritic Spine Synapse Postsynaptic Membrane FAR/SIN/STRIPAK Complex Postsynapse	Chromosome, Telomeric Region Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Nuclear Speck Extracellular Matrix U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Calmodulin Binding Nuclear Estrogen Receptor Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Locomotory Behavior Negative Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Wnt Signaling Pathway Dendrite Development Bicellular Tight Junction Assembly	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Biomineral Tissue Development Negative Regulation Of Protein-containing Complex Assembly Protection From Non-homologous End Joining At Telomere Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Extra-nuclear estrogen signaling Signaling by cytosolic PDGFRA and PDGFRB fusion proteins ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alanine transaminase levels ( 29403010) Appendicular lean mass ( 33097823) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline (age-related) ( 28078323) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Femur bone mineral density x serum urate levels interaction ( 34046847) High light scatter reticulocyte percentage of red cells ( 27863252) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Immature fraction of reticulocytes ( 27863252) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) PR interval ( 32439900) QRS duration ( 27659466 27577874) Red cell distribution width ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549 32154731)
Interacting Genes		12 interacting genes: ATF7IP CALM1 CAV1 ESR1 GNAI1 LNX1 PDCD10 PPP2CA PPP2R1A PPP2R1B RINT1 TFIP11	270 interacting genes: AARD ABI2 ABLIM3 AIMP2 AIRIM ANKRD11 AP1M1 ARHGEF9 ARMC7 ARMCX1 ARNT2 ATP5PO ATPAF2 AXIN1 BAG4 BAZ2B BCAS2 BCL6 BHLHA9 BICD2 BMF BRD1 BYSL CARD9 CATSPERT CAVIN3 CBX8 CCDC102B CCDC116 CCDC120 CCDC121 CCDC13 CCDC146 CCDC187 CCDC196 CCDC42 CCDC57 CCDC6 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CDKN1A CDR2L CENPU CEP55 CEP57 CEP57L1 CEP95 CFAP206 COQ8A COX5B CPEB2 CPSF7 CT55 CWF19L2 DAXX DDX25 DES DGCR6 DHX16 DISC1 DPPA3 DSCAM DTNB EAF2 EIF3A EIF3D ENKD1 ENOX2 EPM2AIP1 EXOC3L1 EXOC8 EXOSC5 EXOSC7 EXOSC8 FAM13C FAM156A FAM161A FAM161B FAM50B FAM81A FAM90A1 FANCG FGA GADD45GIP1 GAS2L2 GCC1 GCFC2 GEM GFAP GNG4 GNL3L GOLGA1 GOLGA2 GPS2 GRAP2 GSE1 HAUS1 HDAC4 HIP1R HMG20B HOOK1 HSF2BP IKBIP IL16 IMP3 JRK KANK2 KANSL1 KAT5 KDM1A KIF20A KIF3C KIF9 KIFC3 KIZ KRT1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5 LCA5L LENG1 LIN37 LMNA LMNB2 LMO1 LMO2 LMO4 LNX1 LSP1P3 LYSMD1 MAB21L2 MAGOH MCM7 MDM2 MED1 METTL17 MFAP1 MKRN3 MRPL11 MTCL2 MTFR2 MYO15B MYO1D MYOM1 NDC80 NDE1 NDN NEK6 NFKBID NFU1 NSMF NUP88 NXF1 ODAD3 OIP5 PBX3 PBX4 PCM1 PDE4DIP PHF1 PIBF1 PICK1 PKN3 PLK4 POLL POLR1C POM121 PPFIA3 PPP1R16A PPP1R16B PPP1R18 PRC1 PRPF18 PRPF31 PRPF6 PSMA4 PSMC5 PSTPIP1 PTCD1 RBBP6 RBM22 RBM7 RCOR3 RHNO1 RIN1 RNF10 RNF6 RPL23A RPUSD3 RRP7A RUNX1T1 RXRB S100P SAP30BP SCNM1 SF1 SFPQ SFR1 SGF29 SH2D4A SH3GLB1 SHANK3 SMARCB1 SMARCE1 SNAPIN SNRNP48 SNRPA SNRPB SNRPN SNW1 SNX20 SNX32 SPG21 SSX2IP STRA8 STRN SUGP1 SYCE1 TBC1D30 TBRG4 TCAF1 TDP2 TFPT THAP7 THAP8 THOC1 TNNT1 TP53 TRAF3IP3 TRAPPC4 TRIM45 TRIML2 TSC1 TSG101 TSGA10IP TSHZ2 TSHZ3 TSPYL4 TUFT1 TXLNA TXN2 UBTFL1 UNKL USP2 USP6 USP7 UTP14A UTP6 VPS37C VPS39 WAC WASHC3 WBP4 ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZNF572 ZNF587 ZNF777 ZSCAN12
Entrez ID		6801	24144
HPRD ID		18124	11628
Ensembl ID		ENSG00000115808	ENSG00000100109
Uniprot IDs		O43815	Q9UBB9
PDB IDs			8RO2
Enriched GO Terms of Interacting Partners?		FAR/SIN/STRIPAK Complex Protein Phosphatase Type 2A Complex Meiotic Sister Chromatid Cohesion, Centromeric Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Meiotic Sister Chromatid Cohesion Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cell Communication By Electrical Coupling Intracellular Signal Transduction INTAC Complex Regulation Of Cell Cycle Process RNA Polymerase II Transcription Initiation Surveillance Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Hippo Signaling Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Extrinsic Apoptotic Signaling Pathway Protein Kinase Binding T Cell Homeostasis Nuclear RNA Surveillance Membrane Raft Fibroblast Proliferation RNA Surveillance Sister Chromatid Cohesion Protein Phosphatase Regulator Activity Regulation Of Hippo Signaling Transcription Elongation By RNA Polymerase II Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cell Cycle Regulation Of Cell Communication Regulation Of Muscle System Process Regulation Of Signaling Inward Rectifier Potassium Channel Inhibitor Activity Negative Regulation Of Endothelial Cell Proliferation RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity DNA-templated Transcription Elongation RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Meiotic Spindle Elongation Regulation Of Action Potential Regulation Of Nitric Oxide Biosynthetic Process Response To Estrogen Lymphocyte Homeostasis Regulation Of Nitric Oxide Metabolic Process Transcription By RNA Polymerase II Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction Response To Metal Ion	Protein Binding Centrosome Cytoskeleton Spliceosomal Complex Microtubule-based Process Nucleoplasm Nucleus MRNA Metabolic Process MRNA Processing Microtubule Cytoskeleton Organization MRNA Splicing, Via Spliceosome Cytoskeleton Organization Nuclear Speck RNA Splicing, Via Transesterification Reactions RNA Splicing Organelle Organization RNA Processing RNA Metabolic Process Cytoplasm Microtubule Organizing Center Organization Nucleic Acid Metabolic Process Centriole Nucleolus U4/U6 X U5 Tri-snRNP Complex SnRNP Binding Cilium Organization Cellular Component Assembly Identical Protein Binding Microtubule Regulation Of Vitamin D Receptor Signaling Pathway U2-type Precatalytic Spliceosome Microtubule Binding General Transcription Initiation Factor Binding Microtubule Anchoring Microtubule Anchoring At Microtubule Organizing Center Nuclear Matrix Macromolecule Metabolic Process Chromatin Organization Kinesin Complex Exoribonuclease Complex Centrosome Cycle Intermediate Filament Cytoskeleton Epigenetic Regulation Of Gene Expression P53 Binding DNA-binding Transcription Factor Binding Intermediate Filament Organization Microtubule-based Movement Structural Constituent Of Cytoskeleton U4 SnRNA 3'-end Processing Intermediate Filament
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?