STAU1 and NCL

Number of citations of the paper that reports this interaction (PMID 15121898)
40

Data Source:
HPRD (in vitro)

		STAU1	NCL
Gene Name		staufen double-stranded RNA binding protein 1	nucleolin
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Microtubule Associated Complex Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cell Cortex Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell	Angiogenesis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		39 interactors: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TUBB TUBB4A UBE2D3 UPF1 ZMAT3	48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		6780	4691
HPRD ID		03422	01245
Ensembl ID		ENSG00000124214
Uniprot IDs		B3KRE0 O95793 Q6PJX3	B3KM80 P19338 Q9BQ02
PDB IDs		4DKK	2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Intracellular Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Localization RNA Transport Cytoskeleton-dependent Intracellular Transport RNA Localization Viral Process Establishment Of Localization In Cell MRNA Processing Viral Transcription SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Protein Complex Disassembly Cotranslational Protein Targeting To Membrane Protein Targeting To ER Viral Life Cycle Neuron Projection Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Catabolic Process Protein Complex Disassembly RNA Splicing Cytoplasmic Transport MRNA Transport Axonogenesis Organelle Transport Along Microtubule Protein Localization To Endoplasmic Reticulum Translational Initiation Microtubule-based Transport Movement Of Cell Or Subcellular Component Microtubule-based Process Axon Development RNA Processing Translational Termination Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of Translation Cell Projection Morphogenesis Protein Targeting To Membrane RNA Export From Nucleus Cell Part Morphogenesis Translational Elongation MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Microtubule-based Movement Developmental Cell Growth	Chromosome Organization DNA Conformation Change Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Chromatin Organization Response To Stimulus Nucleobase-containing Compound Metabolic Process Cellular Response To Stress DNA Packaging Cellular Response To Stimulus Developmental Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Gene Expression Regulation Of Apoptotic Process Chromatin Assembly Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Cell Death Chromatin Assembly Or Disassembly Response To Stress Mitotic Cell Cycle Checkpoint Regulation Of Cell Proliferation DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Aging Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process RNA Biosynthetic Process Cellular Senescence Double-strand Break Repair Protein Complex Assembly DNA Damage Checkpoint Cell Cycle Process Regulation Of RNA Metabolic Process Mitotic Cell Cycle Process
Tagcloud ?		activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored	affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Difference) ?		activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored	affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Intersection) ?