STAU1 and NXT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		STAU1	NXT1
Description		staufen double-stranded RNA binding protein 1	nuclear transport factor 2 like export factor 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Microtubule Associated Complex Plasma Membrane Cytoplasmic Stress Granule Membrane Dendrite Dendrite Cytoplasm Protein-containing Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Neuronal Cell Body Cell Body Extracellular Exosome Glutamatergic Synapse	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Pore Central Transport Channel
	Molecular Function	RNA Binding Double-stranded RNA Binding MRNA Binding Protein Binding Protein Phosphatase 1 Binding	Protein Binding Small GTPase Binding
	Biological Process	LncRNA-mediated Post-transcriptional Gene Silencing Germ Cell Development Intracellular MRNA Localization Cellular Response To Oxidative Stress Protein Localization To Synapse Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Modulation Of Chemical Synaptic Transmission Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Modification Of Postsynaptic Structure Positive Regulation Of Long-term Synaptic Potentiation	RNA Export From Nucleus MRNA Export From Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Anger ( 24489884) Appendicular lean mass ( 33097823) Change in quality of life in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Crohn's disease ( 32581322) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Height ( 28552196 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889 31518406) Loneliness (MTAG) ( 29970889) Waist circumference adjusted for body mass index ( 28552196)	Obesity-related traits ( 23251661)
Interacting Genes		49 interacting genes: ADARB1 APP CASC3 CDC42 CEBPA CFTR CSNK2B DHX9 DYNC1I1 FMR1 FOXP1 GLRX3 HNRNPU INA IQGAP1 KIF2B LINC00624 LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NEIL3 NKRF NXT1 OGT PABPC1 PABPN1 PPP1CA RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 STRBP TAX1BP3 TINCR TUBB TUBB4A UBE2D3 UPF1 USP7 ZMAT3	8 interacting genes: DDOST FBXO16 NXF1 NXF2 NXF3 RAN STAU1 XPO1
Entrez ID		6780	29107
HPRD ID		03422	16159
Ensembl ID		ENSG00000124214	ENSG00000132661
Uniprot IDs		B3KRE0 O95793 Q59F99 Q6PJX3	Q9UKK6
PDB IDs		4DKK 6HTU 6SDW 6SDY	1JKG 1JN5 4WYK 6E5U
Enriched GO Terms of Interacting Partners?		Cytoplasmic Ribonucleoprotein Granule Ribonucleoprotein Complex RNA Binding Cytosol Cytoplasm Nucleus Regulation Of Translation Regulation Of MRNA Metabolic Process MRNA Export From Nucleus Dendrite MRNA Transport Regulation Of Protein Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Processing RNA Export From Nucleus RNA Transport Postsynapse Negative Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Viral Process Cytoskeleton-dependent Intracellular Transport Cytoplasmic Translation Nuclear Export Negative Regulation Of Metabolic Process Nucleobase-containing Compound Transport Negative Regulation Of Macromolecule Metabolic Process Regulation Of Viral Process MRNA Processing Cell Body Regulation Of Cytoplasmic Translation CRD-mediated MRNA Stabilization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleic Acid Metabolic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Protein-containing Complex Binding MRNA Binding Cytosolic Ribosome Positive Regulation Of Supramolecular Fiber Organization Transport Along Microtubule Regulation Of Supramolecular Fiber Organization Nuclear-transcribed MRNA Catabolic Process Cellular Localization Regulation Of RNA Splicing Regulation Of Viral Life Cycle Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation	RNA Export From Nucleus Nuclear Export RNA Transport Nuclear RNA Export Factor Complex Nucleobase-containing Compound Transport MRNA Export From Nucleus Nuclear Transport Nucleocytoplasmic Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Nuclear Export Signal Receptor Activity Cellular Localization RNA Binding Ribosomal Subunit Export From Nucleus Establishment Of Localization In Cell Protein Export From Nucleus Nuclear Envelope Nuclear Pore RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Stress Granule Cellular Response To Triglyceride Regulation Of Nucleocytoplasmic Transport Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex RNA Import Into Nucleus Positive Regulation By Virus Of Viral Protein Levels In Host Cell Response To Triglyceride Nucleic Acid Binding Regulation Of Intracellular Protein Transport LncRNA-mediated Post-transcriptional Gene Silencing Annulate Lamellae Cellular Response To Salt Protein Localization To Nucleus Oligosaccharyltransferase Complex B Germ Cell Development Oligosaccharyltransferase Complex A Pre-miRNA Binding Protein-containing Complex Importin-alpha Family Protein Binding Protein Domain Specific Binding Cellular Response To Mineralocorticoid Stimulus Protein Localization To Nucleolus Intracellular Protein Localization Anterograde Dendritic Transport Intracellular MRNA Localization Nuclear Inclusion Body
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