STAU1 and TUBB4A

Number of citations of the paper that reports this interaction (PMID 15121898)
40

Data Source:
HPRD (in vitro)

		STAU1	TUBB4A
Gene Name		staufen double-stranded RNA binding protein 1	tubulin, beta 4A class IVa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Microtubule Associated Complex Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Vesicular Exosome	Nucleus Cytosol Microtubule Cilium Internode Region Of Axon Neuronal Cell Body Myelin Sheath Extracellular Vesicular Exosome
	Molecular Function	Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding Poly(A) RNA Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Folding Organelle Organization Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport
Pathways			Transport of connexons to the plasma membrane Hedgehog 'off' state Formation of tubulin folding intermediates by CCT/TriC Regulation of PLK1 Activity at G2/M Transition Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Gap junction trafficking and regulation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Gap junction assembly Gap junction trafficking Factors involved in megakaryocyte development and platelet production Resolution of Sister Chromatid Cohesion Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes M Phase Intraflagellar transport Post-chaperonin tubulin folding pathway Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Protein folding Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Signaling by Hedgehog Chaperonin-mediated protein folding Centrosome maturation
Drugs			Epothilone D Epothilone B
Diseases
GWAS
Protein-Protein Interactions		39 interactors: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TUBB TUBB4A UBE2D3 UPF1 ZMAT3	5 interactors: BMPR2 CLN8 NR4A1 STAU1 YWHAG
Entrez ID		6780	10382
HPRD ID		03422	04045
Ensembl ID		ENSG00000124214	ENSG00000104833
Uniprot IDs		B3KRE0 O95793 Q6PJX3	B4DJ43 P04350
PDB IDs		4DKK
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Intracellular Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Localization RNA Transport Cytoskeleton-dependent Intracellular Transport RNA Localization Viral Process Establishment Of Localization In Cell MRNA Processing Viral Transcription SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Protein Complex Disassembly Cotranslational Protein Targeting To Membrane Protein Targeting To ER Viral Life Cycle Neuron Projection Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Catabolic Process Protein Complex Disassembly RNA Splicing Cytoplasmic Transport MRNA Transport Axonogenesis Organelle Transport Along Microtubule Protein Localization To Endoplasmic Reticulum Translational Initiation Microtubule-based Transport Movement Of Cell Or Subcellular Component Microtubule-based Process Axon Development RNA Processing Translational Termination Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of Translation Cell Projection Morphogenesis Protein Targeting To Membrane RNA Export From Nucleus Cell Part Morphogenesis Translational Elongation MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Microtubule-based Movement Developmental Cell Growth	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Endothelial Cell Proliferation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Size Negative Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation L-glutamate Uptake Involved In Synaptic Transmission Positive Regulation Of Epithelial Cell Proliferation Retina Development In Camera-type Eye Negative Regulation Of Protein Metabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Vasoconstriction Age-dependent Response To Oxidative Stress Regulation Of Epithelial Cell Proliferation Somatic Motor Neuron Differentiation Negative Regulation Of Transferase Activity Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation L-glutamate Import Regulation Of Cellular Component Size Cell Differentiation Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Intracellular MRNA Localization Camera-type Eye Development Negative Regulation Of Protein Processing Lymphangiogenesis Regulation Of Cell Death Generation Of Neurons Neurotransmitter Uptake Eye Development Regulation Of Protein Processing Lymph Vessel Morphogenesis Neurofilament Cytoskeleton Organization Endothelial Cell Chemotaxis Neurogenesis Neuromuscular Process Controlling Posture Tissue Development Regulation Of Axon Extension Involved In Axon Guidance Amino Acid Import Venous Blood Vessel Development System Development Intracellular Signal Transduction Cell Migration Involved In Sprouting Angiogenesis Blood Vessel Development Positive Regulation Of Viral Genome Replication
Tagcloud ?		activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Difference) ?		activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Intersection) ?