STAT3 and LCK

  • Number of citations of the paper that reports this interaction (PMID 10825200)
  • 7
  • Data Source:
  • HPRD (in vivo)

STAT3

LCK

Gene Name signal transducer and activator of transcription 3 (acute-phase response factor) LCK proto-oncogene, Src family tyrosine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 161 interactors: ADRB2 AMBP AR ARFIP2 ASXL1 BCKDK BHLHE40 BICD1 BLK BMX BRCA1 CAPN1 CAPNS1 CCND1 CCR1 CCR5 CDK9 CDKN1A CEP120 CORO1A CREBBP CSF2RB CSF3R CXCR4 DAXX ECH1 EGFR EIF2AK2 ELP2 EP300 EPHA3 ERBB2 ERBB2IP FER FES FGFR3 FGFR4 FGR FHL2 FLT1 FOXM1 FYN GATA1 GATA2 GHR GNB2L1 GNL3 GTF2I HCK HDAC1 HDAC2 HDAC3 HES1 HES5 HIC1 HIF1A HIVEP1 HLA-A HNF1A HNRNPM HOXC11 HSP90AA1 HSP90AB1 IFNAR1 IFNAR2 IGF1R IL1RAP IL22RA1 IL23R IL2RA IL2RB IL6R IL6ST IL7R IRAK1 JAK1 JAK2 JAK3 JUN KAT5 KDM1A KHDRBS1 KPNA1 KPNA6 LAMB2 LCK LEP LEPR LMO2 LYN MAP3K13 MAP3K7 MAPK1 MAPK3 MAPK8 MET MORC4 MRPS31 MTOR MYOD1 NCOA1 NDUFA13 NFKB1 NFKBIZ NIF3L1 NLK NMI NR3C1 NR4A1 OGDHL PCBD2 PDGFRA PDGFRB PDIA3 PELP1 PIAS3 PML PRKCD PTK2B PTMA PTPN1 PTPN11 PTPN2 RAC1 RB1 RELA RET RPA2 RPL11 RPS6KA5 RPS9 SCAF11 SETD7 SIAH1 SIAH2 SIN3A SMARCA4 SPRY1 SRC SRI SRRT SS18L1 SSSCA1 STAP2 STAT1 STAT4 STAT5A STAT5B STAT6 STMN1 SULT2A1 SUMO4 SUPT20H SYK TRIM28 TRIP10 TSHR TSLP ZFPM2 ZNF148 ZNF467 122 interactors: ACP1 ADAM15 AJUBA ARHGAP17 AXL BCAR1 BRCA1 CBL CCR5 CD2 CD247 CD28 CD38 CD3E CD4 CD44 CD48 CD5 CD55 CD79A CD79B CD8A CDC25C CDC42 CDKAL1 CSF2RB CSF3R CSK CSNK2B CTLA4 CTNND1 CTNND2 DAPP1 DEF6 DLG1 DOK1 DOK2 DOK3 ESR1 ESR2 EZR FAM174A FAS FASLG FCGR3A G3BP1 GAB2 GRAP HSP90AA1 IFNAR1 IKBKG IL2RB ITK JAK3 KHDRBS1 KIR2DL3 KIT LAT LAX1 LCP2 LIME1 LZTS2 MAPK1 MAPK3 MED28 MS4A1 MUC1 NEDD9 NFKBIA NOTCH1 NR2F2 NR3C1 PAG1 PAK2 PECAM1 PI4KA PIK3CA PIK3R1 PLCG1 PLCG2 PLD2 PRKACA PRKCA PRKCD PRKCQ PTK2 PTK2B PTPN11 PTPN22 PTPN6 PTPRC PTPRF PTPRH PXN RAF1 RASA1 SH2B3 SH2D1A SH2D2A SH3BP2 SHC1 SIT1 SKAP1 SMAD2 SMAD3 SOS1 SQSTM1 STAT1 STAT3 STAT5A SYK THY1 TRAT1 TRPV4 TUB UBE3A UHRF2 UNC119 VAV1 WAS WASL ZAP70
Entrez ID 6774 3932
HPRD ID 00026 01080
Ensembl ID ENSG00000168610 ENSG00000182866
Uniprot IDs K7ENL3 P40763 P06239
PDB IDs 1BHF 1BHH 1CWD 1CWE 1FBZ 1H92 1IJR 1KIK 1LCJ 1LCK 1LKK 1LKL 1Q68 1Q69 1QPC 1QPD 1QPE 1QPJ 1X27 2IIM 2OF2 2OF4 2OFU 2OFV 2OG8 2PL0 2ZM1 2ZM4 2ZYB 3AC1 3AC2 3AC3 3AC4 3AC5 3AC8 3ACJ 3ACK 3AD4 3AD5 3AD6 3B2W 3BRH 3BYM 3BYO 3BYS 3BYU 3KMM 3KXZ 3LCK 3MPM 4D8K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1r  a25  ang  angiotensin  at1  bfgf  cho  constructs  dependently  dominant  fibroblast  ikappabalpha  janus  jun  mek  mek1  messengers  modulators  overexpress  pathophysiological  raf  ras  redox  shared  stat1  stimulatory  transcriptionally  transfection  transiently  tyrphostin 
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
Tagcloud (Difference) ?
1r  a25  ang  angiotensin  at1  bfgf  cho  constructs  dependently  dominant  fibroblast  ikappabalpha  janus  jun  mek  mek1  messengers  modulators  overexpress  pathophysiological  raf  ras  redox  shared  stat1  stimulatory  transcriptionally  transfection  transiently  tyrphostin 
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
Tagcloud (Intersection) ?