SPN and DAXX

Number of citations of the paper that reports this interaction (PMID 11773067)
4

Data Source:
HPRD (two hybrid)

		SPN	DAXX
Gene Name		sialophorin	death-domain associated protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Uropod Basement Membrane Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Extracellular Vesicular Exosome	Chromosome, Centromeric Region Heterochromatin Nucleus Nucleolus Cytoplasm Cytosol PML Body SWI/SNF Superfamily-type Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	P53 Binding Transcription Corepressor Activity Receptor Signaling Protein Activity Protein Binding Transcription Factor Binding Enzyme Binding Protein Kinase Binding Protein Kinase Activator Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Protein Homodimerization Activity Protein N-terminus Binding Androgen Receptor Binding
	Biological Process	Response To Protozoan Negative Regulation Of Type IV Hypersensitivity Positive Regulation Of Protein Phosphorylation Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Surface Receptor Signaling Pathway Blood Coagulation T Cell Costimulation Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Negative Thymic T Cell Selection Regulation Of Defense Response To Virus Leukocyte Migration Apoptotic Signaling Pathway	Mitotic Cytokinesis Positive Regulation Of Protein Phosphorylation Nucleosome Assembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Activation Of JUN Kinase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Viral Process Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neuron Death Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 MSN SIGLEC1	82 interactors: AIRE AR ATM ATRX BTBD6 CA12 CALCOCO2 CARD9 CARM1 CBS CDCA7L CENPC CFLAR CREBBP DAPK3 DMAP1 DNMT1 ESRRG ETS1 FAM9B FANCA FAS FASLG FTH1 GOLGA2 H3F3A HABP4 HBA1 HDAC1 HDAC2 HDAC3 HIPK1 HIPK2 HIPK3 HIST1H3C HIST1H4F HIST4H4 HSF1 HSPB1 MAP3K5 MCRS1 MDM2 MST1 MX1 MYH11 NECAB2 NR3C1 PARK7 PAX3 PAX5 PBXIP1 PLAGL1 PML PRMT1 RASSF1 RPL13 SENP2 SERBP1 SLC2A4 SLC9A1 SNW1 SPN SPOP SSX2IP STAT3 STUB1 SUMO1 TCF3 TCF7L2 TGFB1 TGFB2 TGFBR2 TNFRSF1A TP53 TP63 TP73 TRAF3 TRIM21 TSG101 UBE2I USP7 WHSC1L1
Entrez ID		6693	1616
HPRD ID		06770	04424
Ensembl ID		ENSG00000197471	ENSG00000204209
Uniprot IDs		A8K9B1 P16150	B4E1C1 F5ANJ6 F5ANJ7 Q53F85 Q9UER7
PDB IDs			2KQS 2KZS 2KZU 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Barrier Membrane To Membrane Docking Endothelial Cell Development Single Organismal Cell-cell Adhesion Endothelial Cell Differentiation Endothelium Development Leukocyte Cell-cell Adhesion Epithelial Cell Development Cell Adhesion Positive Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Membrane Docking Lymphocyte Activation Regulation Of Cell Morphogenesis Leukocyte Activation Response To Drug Regulation Of Cell Shape Epithelial Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Locomotion Regulation Of Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Adhesion Cell Activation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Movement Of Cell Or Subcellular Component Leukocyte Migration Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Signal Transduction Androgen Receptor Signaling Pathway T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Myoblast Differentiation Regulation Of Neuron Death Cell Migration Regulation Of T Cell Activation Regulation Of Intracellular Signal Transduction Regulation Of Signaling Cell Development Cell Motility Homotypic Cell-cell Adhesion Regulation Of Cellular Component Organization Cellular Response To Glucose Stimulus Cell Differentiation Regulation Of Cell-cell Adhesion Response To Stress	Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Stress Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cell Death Regulation Of Signal Transduction Death Apoptotic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Gene Expression Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Programmed Cell Death Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Signaling Transcription, DNA-templated Cellular Response To Stress Cellular Aromatic Compound Metabolic Process Chromatin Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Process Response To Stimulus Chromosome Organization Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle
Tagcloud ?			adaptor appear characterization convey death domains effector fadd far growing homologies insights isolation jun mammalian members mort necrosis represents rip seem share signals superfamily tnfr tradd traf traf1 transmit
Tagcloud (Difference) ?			adaptor appear characterization convey death domains effector fadd far growing homologies insights isolation jun mammalian members mort necrosis represents rip seem share signals superfamily tnfr tradd traf traf1 transmit
Tagcloud (Intersection) ?