DAXX and MYH11

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		DAXX	MYH11
Gene Name		death-domain associated protein	myosin, heavy chain 11, smooth muscle
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Heterochromatin Nucleus Nucleolus Cytoplasm Cytosol PML Body SWI/SNF Superfamily-type Complex	Stress Fiber Cytosol Muscle Myosin Complex Smooth Muscle Contractile Fiber Myosin Filament Melanosome Extracellular Vesicular Exosome
	Molecular Function	P53 Binding Transcription Corepressor Activity Receptor Signaling Protein Activity Protein Binding Transcription Factor Binding Enzyme Binding Protein Kinase Binding Protein Kinase Activator Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Protein Homodimerization Activity Protein N-terminus Binding Androgen Receptor Binding	Motor Activity Protein Binding Calmodulin Binding ATP Binding Structural Constituent Of Muscle Actin Filament Binding
	Biological Process	Mitotic Cytokinesis Positive Regulation Of Protein Phosphorylation Nucleosome Assembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Activation Of JUN Kinase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Viral Process Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neuron Death Positive Regulation Of Apoptotic Signaling Pathway	Muscle Contraction Smooth Muscle Contraction Axon Guidance Metabolic Process Skeletal Muscle Myosin Thick Filament Assembly Ephrin Receptor Signaling Pathway Elastic Fiber Assembly Cardiac Muscle Fiber Development
Pathways			EPHA-mediated growth cone collapse Axon guidance Semaphorin interactions Smooth Muscle Contraction EPH-Ephrin signaling Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		82 interactors: AIRE AR ATM ATRX BTBD6 CA12 CALCOCO2 CARD9 CARM1 CBS CDCA7L CENPC CFLAR CREBBP DAPK3 DMAP1 DNMT1 ESRRG ETS1 FAM9B FANCA FAS FASLG FTH1 GOLGA2 H3F3A HABP4 HBA1 HDAC1 HDAC2 HDAC3 HIPK1 HIPK2 HIPK3 HIST1H3C HIST1H4F HIST4H4 HSF1 HSPB1 MAP3K5 MCRS1 MDM2 MST1 MX1 MYH11 NECAB2 NR3C1 PARK7 PAX3 PAX5 PBXIP1 PLAGL1 PML PRMT1 RASSF1 RPL13 SENP2 SERBP1 SLC2A4 SLC9A1 SNW1 SPN SPOP SSX2IP STAT3 STUB1 SUMO1 TCF3 TCF7L2 TGFB1 TGFB2 TGFBR2 TNFRSF1A TP53 TP63 TP73 TRAF3 TRIM21 TSG101 UBE2I USP7 WHSC1L1	4 interactors: APC DAXX GRB2 MAPKAPK5
Entrez ID		1616	4629
HPRD ID		04424	01174
Ensembl ID		ENSG00000204209	ENSG00000133392
Uniprot IDs		B4E1C1 F5ANJ6 F5ANJ7 Q53F85 Q9UER7	P35749
PDB IDs		2KQS 2KZS 2KZU 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Stress Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cell Death Regulation Of Signal Transduction Death Apoptotic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Gene Expression Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Programmed Cell Death Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Signaling Transcription, DNA-templated Cellular Response To Stress Cellular Aromatic Compound Metabolic Process Chromatin Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Process Response To Stimulus Chromosome Organization Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle	Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Mitotic Cytokinesis Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Regulation Of Intracellular Signal Transduction Cytokinesis Regulation Of Protein Kinase Activity Positive Regulation Of Protein Polymerization Regulation Of Kinase Activity Regulation Of Signal Transduction Activation Of MAPK Activity Regulation Of Signaling Positive Regulation Of Protein Complex Assembly Protein Complex Assembly Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Metabolic Process Response To Stress Negative Regulation Of Signaling Positive Regulation Of MAP Kinase Activity Ras Protein Signal Transduction Positive Regulation Of Protein Metabolic Process MAPK Cascade Negative Regulation Of Odontogenesis Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Component Biogenesis Metaphase/anaphase Transition Of Mitotic Cell Cycle Aging Regulation Of Protein Complex Assembly Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Organelle Organization Negative Regulation Of Intracellular Signal Transduction Stress-induced Premature Senescence Cell Division Intracellular Signal Transduction Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Cellular Component Assembly Positive Regulation Of MAPK Cascade Positive Regulation Of Pseudopodium Assembly Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		adaptor appear characterization convey death domains effector fadd far growing homologies insights isolation jun mammalian members mort necrosis represents rip seem share signals superfamily tnfr tradd traf traf1 transmit	abi1 atlas bitbucket ccnd3 ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Difference) ?		adaptor appear characterization convey death domains effector fadd far growing homologies insights isolation jun mammalian members mort necrosis represents rip seem share signals superfamily tnfr tradd traf traf1 transmit	abi1 atlas bitbucket ccnd3 ctnnd1 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript
Tagcloud (Intersection) ?