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SPN and SIGLEC1
Number of citations of the paper that reports this interaction (PubMedID
11238599
)
0
Data Source:
HPRD
(in vivo)
SPN
SIGLEC1
Description
sialophorin
sialic acid binding Ig like lectin 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Uropod
Basement Membrane
Extracellular Space
Nucleus
Plasma Membrane
Microvillus
External Side Of Plasma Membrane
Cell Surface
Membrane
PML Body
Cell Projection
Extracellular Exosome
Extracellular Region
Early Endosome
Late Endosome
Plasma Membrane
Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Hsp70 Protein Binding
Heat Shock Protein Binding
Carbohydrate Binding
Virion Binding
Biological Process
Response To Protozoan
Negative Regulation Of Type IV Hypersensitivity
T-helper 1 Cell Lineage Commitment
Chemotaxis
Immune Response
Cellular Defense Response
Negative Regulation Of Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Signal Transduction
Cell Surface Receptor Signaling Pathway
T Cell Costimulation
Positive Regulation Of Tumor Necrosis Factor Production
T Cell Proliferation
Positive Regulation Of T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Negative Thymic T Cell Selection
Regulation Of Defense Response To Virus
Regulation Of Immune Response
Regulation Of T Cell Activation
Negative Regulation Of T Cell Activation
Leukocyte Tethering Or Rolling
Apoptotic Signaling Pathway
Regulation Of T Cell Migration
Positive Regulation Of T Cell Migration
Endocytosis
Inflammatory Response
Cell Adhesion
Cell-matrix Adhesion
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Clathrin-dependent Endocytosis Of Virus By Host Cell
Cell-cell Adhesion
Pathways
Cell surface interactions at the vascular wall
Basigin interactions
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Beta-D-Glucose
N-acetyl-alpha-neuraminic acid
Diseases
GWAS
IgM levels (
28628107
)
Liver enzyme levels (gamma-glutamyl transferase) (
33972514
)
Night sleep phenotypes (
27126917
)
Reticulocyte fraction of red cells (
32888494
)
Visceral fat (
30942860
)
Interacting Genes
18 interacting genes:
ARL13B
CLCA4
CTNNB1
CTSA
CXCL16
CYBC1
DAXX
ERGIC3
EZR
FYN
ICAM1
LGALS1
LMNA
MSN
PLP2
SGTA
SIGLEC1
UBQLN2
3 interacting genes:
MUC1
SPN
TNR
Entrez ID
6693
6614
HPRD ID
06770
02854
Ensembl ID
ENSG00000197471
ENSG00000088827
Uniprot IDs
P16150
Q9BZZ2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Membrane To Membrane Docking
Disordered Domain Specific Binding
Microvillus Membrane
Cell Periphery
Regulation Of Protein Catabolic Process
Cell-cell Adhesion
Establishment Of Endothelial Barrier
T Cell Migration
Endothelial Cell Development
Lymphocyte Migration
Leukocyte Cell-cell Adhesion
Positive Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Protein Localization To Early Endosome
Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Signaling Pathway
Lymphocyte Activation
Leukocyte Migration
Positive Regulation Of Protein Localization To Endosome
Positive Regulation Of Protein Catabolic Process
Uropod
Apical Part Of Cell
Membrane Docking
Layer Formation In Cerebral Cortex
Postsynaptic Density, Intracellular Component
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Early Endosome To Late Endosome Transport
Establishment Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of ERAD Pathway
Cell Adhesion
Mononuclear Cell Migration
Membrane
Cell Migration
Regulation Of Protein Localization
T Cell Activation
Leukocyte Activation
Establishment Of Apical/basal Cell Polarity
Negative Regulation Of Protein Catabolic Process
Polarized Epithelial Cell Differentiation
Establishment Of Monopolar Cell Polarity
Establishment Or Maintenance Of Monopolar Cell Polarity
Regulation Of ERAD Pathway
Epithelial Cell Development
Plasma Membrane
Regulation Of Cell Shape
Positive Regulation Of Intracellular Transport
Gland Morphogenesis
Establishment Of Epithelial Cell Polarity
Cell Activation
Cell Motility
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Extracellular Space
Negative Regulation Of Type IV Hypersensitivity
T-helper 1 Cell Lineage Commitment
Negative Regulation Of Cell-cell Adhesion
Regulation Of Type IV Hypersensitivity
Tenascin Complex
Axon Extension Involved In Regeneration
Neuroblast Migration
Negative Regulation Of Axon Extension Involved In Regeneration
Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Transmission Of Nerve Impulse
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Cellular Response To Stress
Negative Regulation Of Transcription By Competitive Promoter Binding
Mitotic G1/S Transition Checkpoint Signaling
Mitotic G1 DNA Damage Checkpoint Signaling
Negative Regulation Of Cell Adhesion Mediated By Integrin
Cell-cell Adhesion
Negative Regulation Of Acute Inflammatory Response
Regulation Of Cell-cell Adhesion
Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Negative Thymic T Cell Selection
Negative T Cell Selection
Uropod
Locomotory Exploration Behavior
Neuron Cell-cell Adhesion
Regulation Of Transmission Of Nerve Impulse
Negative Regulation Of Axon Regeneration
Negative Regulation Of Neuron Projection Regeneration
Perineuronal Net
T-helper Cell Lineage Commitment
Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Leukocyte Tethering Or Rolling
Thymic T Cell Selection
CD4-positive, Alpha-beta T Cell Lineage Commitment
Leukocyte Adhesion To Vascular Endothelial Cell
Alpha-beta T Cell Lineage Commitment
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cell Surface
CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment
Regulation Of Axon Regeneration
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Response To Protozoan
T Cell Lineage Commitment
T Cell Selection
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of Neuron Projection Regeneration
Negative Regulation Of Axon Extension
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Tagcloud (Intersection)
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