SPN and MSN

Number of citations of the paper that reports this interaction (PMID 9616160)
24

Data Source:
HPRD (in vitro, in vivo)

		SPN	MSN
Gene Name		sialophorin	moesin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Uropod Basement Membrane Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Extracellular Vesicular Exosome	Uropod Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Microvillus Focal Adhesion Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium Microvillus Membrane Vesicle Apical Part Of Cell Extracellular Vesicular Exosome Cell Periphery Blood Microparticle
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Double-stranded RNA Binding Actin Binding Receptor Binding Structural Constituent Of Cytoskeleton Protein Binding Protein Kinase Binding Cell Adhesion Molecule Binding
	Biological Process	Response To Protozoan Negative Regulation Of Type IV Hypersensitivity Positive Regulation Of Protein Phosphorylation Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Surface Receptor Signaling Pathway Blood Coagulation T Cell Costimulation Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Negative Thymic T Cell Selection Regulation Of Defense Response To Virus Leukocyte Migration Apoptotic Signaling Pathway	Movement Of Cell Or Subcellular Component Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression Membrane To Membrane Docking Leukocyte Migration Establishment Of Endothelial Barrier Regulation Of Lymphocyte Migration
Pathways		Basigin interactions Cell surface interactions at the vascular wall	Axon guidance L1CAM interactions Recycling pathway of L1
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 MSN SIGLEC1	24 interactors: BCAP31 CD44 CD46 CD93 CDK11B EZR ICAM1 ICAM2 ICAM3 L1CAM NCF1 NCF4 PLEC PPM1A PPM1B PRKCQ ROCK1 SELL SELPLG SLC9A3R1 SPN TERF1 TSC1 VCAM1
Entrez ID		6693	4478
HPRD ID		06770	02399
Ensembl ID		ENSG00000197471	ENSG00000147065
Uniprot IDs		A8K9B1 P16150	P26038
PDB IDs			1E5W 1EF1 1SGH
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Barrier Membrane To Membrane Docking Endothelial Cell Development Single Organismal Cell-cell Adhesion Endothelial Cell Differentiation Endothelium Development Leukocyte Cell-cell Adhesion Epithelial Cell Development Cell Adhesion Positive Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Membrane Docking Lymphocyte Activation Regulation Of Cell Morphogenesis Leukocyte Activation Response To Drug Regulation Of Cell Shape Epithelial Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Locomotion Regulation Of Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Adhesion Cell Activation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Movement Of Cell Or Subcellular Component Leukocyte Migration Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Signal Transduction Androgen Receptor Signaling Pathway T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Myoblast Differentiation Regulation Of Neuron Death Cell Migration Regulation Of T Cell Activation Regulation Of Intracellular Signal Transduction Regulation Of Signaling Cell Development Cell Motility Homotypic Cell-cell Adhesion Regulation Of Cellular Component Organization Cellular Response To Glucose Stimulus Cell Differentiation Regulation Of Cell-cell Adhesion Response To Stress	Membrane To Membrane Docking Single Organismal Cell-cell Adhesion Cell Adhesion Leukocyte Migration Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Positive Regulation Of Cell Adhesion Immune System Process Regulation Of Cell Adhesion Positive Regulation Of T Cell Proliferation Cellular Extravasation Membrane Docking Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Immune Response Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Cell-cell Adhesion Locomotion Regulation Of Immune System Process Regulation Of T Cell Proliferation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Execution Phase Of Apoptosis Cell Migration Regulation Of Cell-cell Adhesion Cell Motility Positive Regulation Of T Cell Activation Cell Surface Receptor Signaling Pathway Immune Response Apoptotic Process Blood Coagulation Inflammatory Response Hemostasis Cell Activation Programmed Cell Death Cell Death Death Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Signal Transduction Leukocyte Activation Interferon-gamma-mediated Signaling Pathway Response To Stimulus Regulation Of T Cell Activation Innate Immune Response Positive Regulation Of Cell Activation Negative Regulation Of Signaling Cellular Response To Interferon-gamma Regulation Of Body Fluid Levels
Tagcloud ?			assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter
Tagcloud (Difference) ?			assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter
Tagcloud (Intersection) ?