SP1 and BRCA1

  • Number of citations of the paper that reports this interaction (PMID 10720440)
  • 10
  • Data Source:
  • HPRD (in vivo, in vitro)

SP1

BRCA1

Gene Name Sp1 transcription factor breast cancer 1, early onset
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 139 interactors: AATF AHR AR ARHGAP21 ARNT ATF7IP ATF7IP2 BCL11B BCL6 BCOR BRCA1 BTRC C3orf17 CASP3 CASP6 CASP7 CBX5 CCNA1 CCNA2 CCND1 CD2 CDK1 CDK2 CEBPB CSNK2A1 DDX5 DROSHA E2F1 E2F2 E2F3 EGR1 ELF1 EP300 ESR1 ESR2 ESRRA ESRRB ESRRG ETS1 GABPA GATA1 GATA3 GATA4 HBZ HCFC1 HDAC1 HDAC2 HIF1A HINT1 HLTF HMGA1 HNF4A HOXC11 HSPA8 HTT IL1B JUN KIF1A KLF10 KLF4 KLF6 LDB1 LMO2 MAPK1 MAPK3 MAPK8 MEF2C MEF2D MIER1 MIS18BP1 MSX1 MYC MYCN MYOD1 MYOG NAP1L1 NCOR1 NCOR2 NFKB1 NFKB2 NFYA NFYB NFYC NKX3-1 NOS3 NR2F1 NR5A1 NUP62 OGT PARP1 PER3 PML POGZ POU2F1 PPIG PPP1R13L PRKCZ PRKDC PSIP1 PSMC5 PURA RARA RB1 RBBP4 RBL1 REL RELA RNF4 RXRA SENP6 SF3A1 SHC1 SKIV2L2 SMAD2 SMAD3 SMAD4 SMARCC1 SMARCC2 SOX10 SOX8 SP3 SP4 SREBF1 SREBF2 SRF SUB1 SUMO1 TAF4 TAL1 TBP TFAP2A TLX3 TP53 TPI1 USP39 VHL YY1 ZBTB16 ZBTB7A 312 interactors: ABL1 ABLIM3 ACACA ACTG1 ACTN3 AHR AKT1 ALDH1A1 ALS2CR11 ANTXR1 AP1M1 APLP2 AR ARNT ASH2L ATF1 ATM ATP1B1 ATP1B3 ATR ATRIP AURKA AURKC BABAM1 BAP1 BARD1 BRAP BRAT1 BRCA2 BRCC3 BRIP1 BRSK1 C22orf29 CABYR CASP3 CCDC120 CCNA1 CCNA2 CCNB1 CCND1 CDK1 CDK16 CDK2 CDK4 CDK5 CDK7 CDK9 CDKN2D CEP57L1 CHEK1 CHEK2 CLSPN CNRIP1 CNTLN CNTN4 COL1A1 COMMD1 CREBBP CRIPAK CRY2 CRYZL1 CSNK1D CSNK2A1 CSNK2B CSTF1 CTBP1 CTCFL CTNNB1 CUBN CWF19L2 DALRD3 DBF4 DCLRE1C DCN DDX24 DES DHPS DHX9 DNAJA1 DNAJA3 DNAJB1 DNHD1 DYNC1H1 E2F1 E2F4 EED EIF3B EIF4A2 EIF5B ELK1 ELK4 ENO1 EP300 ERCC6 ERO1LB ESR1 ETS1 ETV5 EZH2 FAM161A FAM175A FAM184A FANCA FANCD2 FHL2 FLI1 FXR2 GCC1 GFI1B GGN GOLGA8DP GTF3C4 GUSBP1 H2AFX H2AFY HDAC1 HDAC2 HECTD3 HERC2 HGF HIBADH HIST1H2AB HIST2H2AC HIVEP1 HNRNPC HNRNPD HORMAD1 HSPA14 HSPA8 HSPD1 IFI16 INPP1 ITIH5 JAK1 JAK2 JUN JUNB JUND JUP KAT2A KAT5 KDM1A KIF1B KPNA2 KPNA6 LCK LCMT1 LDHC LMNTD1 LMO4 LONRF1 MAN2C1 MAP3K1 MAP3K14 MAP3K3 MAP4K4 MARCKSL1 MDC1 MED1 MED21 MID2 MLH1 MNAT1 MRE11A MSH2 MSH3 MSH6 MYC MYOZ1 NBN NCOA2 NCOA3 ND1 NELFB NFKB1 NFYA NKAPL NMI NPC2 NRIP1 NUFIP1 NUP153 OBSCN OLA1 PEG3 PEX5 PGR PHF12 PIAS1 PIAS4 PIK3R1 PILRB PISD POLR2A POLR2H POLR2K POM121 POMGNT1 POU2F1 PPHLN1 PPP1CA PPP1CB PPP1R13B PPP2R5C PREP PRKAG3 PRKDC PRMT1 PRPF3 PSAP PSMA6 PSMD9 PSMG1 RAD51 RANBP9 RB1 RBBP4 RBBP7 RBBP8 RBL1 RBL2 RBX1 RELA RFC1 RNF216 RPGRIP1 RPL31 RTKN2 RUNX1T1 RWDD2B RWDD4 SDK2 SETX SHFM1 SMAD2 SMAD3 SMAD4 SMARCA2 SMARCA4 SMC1A SNRNP200 SNX3 SNX6 SOX30 SP1 SPATA4 SRC SSFA2 SSX2IP STAC2 STAT1 STAT3 STAT5A SUMO1 SYT6 TARS TATDN2 TCEA2 TCEANC TCEB3 TCTEX1D2 TEX101 THOC3 TLE4 TMPRSS12 TNS2 TOP2A TP53 TP53BP1 TPTE2 TRIM24 TRIM46 TRIM74 TRRAP TSEN54 TSGA10IP TUBA4A TUBB TUBG1 TULP2 TXLNA UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2J1 UBE2K UBE2L3 UBE2N UBE2T UBE2W UBE3A UBXN1 USF2 USH2A USP2 VCP WBSCR16 WDR6 WNT2B XIAP XRCC1 XRCC5 YY1 ZNF280D ZNF350 ZNF423 ZSCAN21
Entrez ID 6667 672
HPRD ID 01796 00218
Ensembl ID ENSG00000185591 ENSG00000012048
Uniprot IDs E4Z9M7 G5E9M8 P08047 E9PFC7 E9PFZ0 P38398 Q1RMC1
PDB IDs 1SP1 1SP2 1VA1 1VA2 1VA3 1JM7 1JNX 1N5O 1OQA 1T15 1T29 1T2U 1T2V 1Y98 2ING 3COJ 3K0H 3K0K 3K15 3K16 3PXA 3PXB 3PXC 3PXD 3PXE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1b  53bp1  activators  associates  binds  brct  cbp  cip1  domain  emphasized  hat  homology  inherited  link  manners  maps  ovarian  p100  p110  p21waf1  p53  promoters  splice  stimulate  stimulates  suppression  transactivation 
Tagcloud (Difference) ?
1b  53bp1  activators  associates  binds  brct  cbp  cip1  domain  emphasized  hat  homology  inherited  link  manners  maps  ovarian  p100  p110  p21waf1  p53  promoters  splice  stimulate  stimulates  suppression  transactivation 
Tagcloud (Intersection) ?