SOX5 and KIFC3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SOX5	KIFC3
Gene Name		SRY (sex determining region Y)-box 5	kinesin family member C3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Transcription Factor Complex	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Central Nervous System Neuron Differentiation Positive Regulation Of Chondrocyte Differentiation Cell Fate Commitment Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Oligodendrocyte Differentiation Cartilage Development Regulation Of Timing Of Neuron Differentiation Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation	Microtubule-based Movement Golgi Organization Visual Perception Metabolic Process Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		AIDS ( 19754311) Non-obstructive azoospermia ( 22197933) PR interval ( 20062060) Response to antipsychotic treatment ( 20195266) Response to statin therapy ( 20339536) Systemic sclerosis ( 21779181)
Protein-Protein Interactions		26 interactors: AES APP ARID5A CBX8 CDC23 CDC25A CDK6 CRX FAM46B FTH1 KAT5 KIFC3 LMO1 LMO2 MED27 MORN3 PRR20A RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TTC1 UQCRFS1 ZNF581	91 interactors: ABI2 AES ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CCDC102B CCDC136 CCDC28A CCDC33 CCDC67 CDK18 CDR2 CEP170P1 CEP55 CEP57L1 CLIP4 CREB5 CYTH4 DCTN2 DCX DTNBP1 ESRRG FAM124A FANCL FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SPERT SVIL SYCE1 TCEANC TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655
Entrez ID		6660	3801
HPRD ID		18086	05171
Ensembl ID		ENSG00000134532	ENSG00000140859
Uniprot IDs		P35711 T2CYZ2	B7Z484 B7Z896 F5H4I9 Q9BVG8
PDB IDs			2H58
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process Osteoblast Fate Commitment Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cartilage Development Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process BMP Signaling Pathway Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Connective Tissue Development Transcription From RNA Polymerase II Promoter Metabolic Process Skeletal System Development Negative Regulation Of Biosynthetic Process Organ Development Cellular Response To BMP Stimulus Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development	Cell Cycle Organelle Organization Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of RNA Metabolic Process Mitotic Cell Cycle RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Gene Expression Cytoskeleton Organization Mitotic Cell Cycle Process RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Developmental Process Axon Cargo Transport Microtubule-based Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Macromolecule Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Binding Regulation Of Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Protein K63-linked Ubiquitination Retrograde Axon Cargo Transport Protein Polyubiquitination Anatomical Structure Development Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Chromosome Organization Protein Monoubiquitination Cellular Nitrogen Compound Metabolic Process Reproduction Heterocycle Metabolic Process Microtubule Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process
Tagcloud ?		aberrantly abrogated alcian atdc5 blue box chondrocyte chondrogenesis chondrogenic clonal delayed determining differentiating diminish drastic evidenced fate hypertrophic l lineage mobility osteoarthritic overexpressing progress proteoglycan retroviral runx2 unaltered	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Difference) ?		aberrantly abrogated alcian atdc5 blue box chondrocyte chondrogenesis chondrogenic clonal delayed determining differentiating diminish drastic evidenced fate hypertrophic l lineage mobility osteoarthritic overexpressing progress proteoglycan retroviral runx2 unaltered	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Intersection) ?