SOX5 and ARID5A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SOX5	ARID5A
Gene Name		SRY (sex determining region Y)-box 5	AT rich interactive domain 5A (MRF1-like)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Transcription Factor Complex	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	DNA Binding Chromatin Binding Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding
	Biological Process	In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Central Nervous System Neuron Differentiation Positive Regulation Of Chondrocyte Differentiation Cell Fate Commitment Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Oligodendrocyte Differentiation Cartilage Development Regulation Of Timing Of Neuron Differentiation Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation	Chondrocyte Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		AIDS ( 19754311) Non-obstructive azoospermia ( 22197933) PR interval ( 20062060) Response to antipsychotic treatment ( 20195266) Response to statin therapy ( 20339536) Systemic sclerosis ( 21779181)	Event-related brain oscillations ( 21184583)
Protein-Protein Interactions		26 interactors: AES APP ARID5A CBX8 CDC23 CDC25A CDK6 CRX FAM46B FTH1 KAT5 KIFC3 LMO1 LMO2 MED27 MORN3 PRR20A RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TTC1 UQCRFS1 ZNF581	18 interactors: AR ATXN1 CKS1B DAB1 DAZAP2 ESR2 GOLGA2 KRT40 KRTAP12-2 KRTAP12-4 MDFI PNMA1 RARA RBPMS RHOXF2 RXRA SOX5 THRA
Entrez ID		6660	10865
HPRD ID		18086	12481
Ensembl ID		ENSG00000134532	ENSG00000196843
Uniprot IDs		P35711 T2CYZ2	C9J1Q0 Q03989
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process Osteoblast Fate Commitment Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cartilage Development Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process BMP Signaling Pathway Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Connective Tissue Development Transcription From RNA Polymerase II Promoter Metabolic Process Skeletal System Development Negative Regulation Of Biosynthetic Process Organ Development Cellular Response To BMP Stimulus Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development	Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Prostate Gland Development DNA-templated Transcription, Initiation Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Cellular Response To Lipid Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Phosphorylation Negative Regulation Of Gene Expression Response To Steroid Hormone Transcription From RNA Polymerase II Promoter Gland Development Reproductive Structure Development Reproductive System Development Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Organ Development Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Developmental Process Involved In Reproduction Regulation Of Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Epithelial Cell Differentiation Involved In Prostate Gland Development Regulation Of Signal Transduction Cytoplasmic Sequestering Of Transcription Factor Reproductive Process Urogenital System Development Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cytoplasmic Sequestering Of Protein Negative Regulation Of Cellular Metabolic Process Response To Lipid Positive Regulation Of Phosphorylation
Tagcloud ?		aberrantly abrogated alcian atdc5 blue box chondrocyte chondrogenesis chondrogenic clonal delayed determining differentiating diminish drastic evidenced fate hypertrophic l lineage mobility osteoarthritic overexpressing progress proteoglycan retroviral runx2 unaltered	10q23 2q11 dependence emerge endophenotype ero eros fisher gwas heritable homozygotes htr7 humanhap illumina implicating intriguing neuroelectrical neurophysiological nominally oscillations revealing rs4907240 rs7916403 serotonergic theta unadjusted underpinnings underscore
Tagcloud (Difference) ?		aberrantly abrogated alcian atdc5 blue box chondrocyte chondrogenesis chondrogenic clonal delayed determining differentiating diminish drastic evidenced fate hypertrophic l lineage mobility osteoarthritic overexpressing progress proteoglycan retroviral runx2 unaltered	10q23 2q11 dependence emerge endophenotype ero eros fisher gwas heritable homozygotes htr7 humanhap illumina implicating intriguing neuroelectrical neurophysiological nominally oscillations revealing rs4907240 rs7916403 serotonergic theta unadjusted underpinnings underscore
Tagcloud (Intersection) ?