GGA1 and ATXN7L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GGA1	ATXN7L1
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	ataxin 7 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Protein Catabolic Process Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Protein Localization To Ciliary Membrane
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)	Alzheimer's disease (late onset) ( 22881374) Blond vs. brown/black hair color ( 30531825) Dental caries ( 23064961) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 28869591 30598549) Obesity-related traits ( 23251661) Smoking cessation in chronic obstructive pulmonary disease ( 29631575)
Interacting Genes		48 interacting genes: ADRA2B AFTPH AP1AR AP1G1 APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CFTR CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR ETS1 F8 GGA2 GGA3 GTPBP4 GTSE1 IGF2R ING5 JUN LRP3 M6PR NPM1 RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TP53 TSG101 UBC VPS18	11 interacting genes: GGA1 KRT31 KRTAP10-9 PHF1 ROR2 SP4 SSPOP TRIM55 TRIM63 VENTX VEZF1
Entrez ID		26088	222255
HPRD ID		12078	12508
Ensembl ID		ENSG00000100083	ENSG00000146776
Uniprot IDs		Q9UJY5	Q9BTQ8 Q9ULK2
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		Early Endosome Endosome Protein Transport Establishment Of Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Intracellular Transport Cellular Localization Endosome Membrane Vacuolar Transport Establishment Of Localization In Cell Clathrin-coated Vesicle Lysosomal Transport Intracellular Protein Localization Trans-Golgi Network Recycling Endosome Endocytosis Golgi Apparatus Early Endosome Membrane Import Into Cell Post-Golgi Vesicle-mediated Transport Establishment Of Protein Localization To Vacuole Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Protein Localization To Vacuole Protein Targeting To Vacuole Positive Regulation Of MiRNA Transcription Receptor-mediated Endocytosis Negative Regulation Of Protein Metabolic Process Trans-Golgi Network Membrane Positive Regulation Of MiRNA Metabolic Process Protein Localization To Organelle Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To Lysosome Enzyme Binding Regulation Of Cell Growth Clathrin-coated Pit Ubiquitin Protein Ligase Binding Retromer Complex Binding Regulation Of Vesicle-mediated Transport Golgi To Lysosome Transport Nuclear Envelope Lumen AP-1 Adaptor Complex Establishment Of Protein Localization To Organelle Late Endosome Regulation Of Cell Cycle Regulation Of Growth Protein-containing Complex
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