GGA1 and AP1AR

Number of citations of the paper that reports this interaction (PMID 15775984)
14

Data Source:
HPRD (in vitro)

		GGA1	AP1AR
Gene Name		golgi-associated, gamma adaptin ear containing, ARF binding protein 1	adaptor-related protein complex 1 associated regulatory protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Endosome Membrane Membrane Clathrin Adaptor Complex Intracellular Membrane-bounded Organelle	Early Endosome Late Endosome Golgi Apparatus Transport Vesicle
	Molecular Function	Molecular_function Protein Binding	Kinesin Binding AP-1 Adaptor Complex Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Positive Regulation Of Protein Catabolic Process	Negative Regulation Of Receptor Recycling Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Protein Localization Vesicle Targeting, Trans-Golgi To Endosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Motility
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: AFTPH AP1AR APP ARF1 ARF3 ARF5 ARF6 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB F8 GGA2 GGA3 IGF2R LRP3 M6PR RAB5A RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TSG101 UBC VPS18	2 interactors: AP1G1 GGA1
Entrez ID		26088	55435
HPRD ID		12078	12824
Ensembl ID		ENSG00000100083	ENSG00000138660
Uniprot IDs		Q6IC75 Q9UJY5	Q63HQ0
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Transport Protein Transport Establishment Of Protein Localization Endocytosis Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Post-Golgi Vesicle-mediated Transport Endosomal Transport Viral Protein Processing Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Protein Processing Regulation Of Cellular Component Organization Cellular Protein Localization Golgi Vesicle Transport Negative Regulation Of Protein Metabolic Process Intracellular Protein Transport Virion Assembly Apoptotic Process Programmed Cell Death Intracellular Transport Of Virus Cell Death Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Membrane Organization Regulation Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Proteolysis Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Lysosomal Transport Positive Regulation Of Proteolysis Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Viral Process Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Growth Regulation Of Endocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Life Cycle Positive Regulation Of Cell Cycle Arrest	Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Intracellular Protein Transport Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Natural Killer Cell Activation Regulation Of Regulated Secretory Pathway Cellular Protein Localization Protein Transport Vesicle-mediated Transport Lysosomal Transport Establishment Of Protein Localization Intracellular Transport Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation Protein Localization Vacuolar Transport Regulation Of Defense Response To Virus Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Pigmentation Cellular Localization Regulation Of Exocytosis Positive Regulation Of Innate Immune Response Endosomal Transport Vesicle Organization Positive Regulation Of Protein Catabolic Process Antigen Processing And Presentation Of Peptide Antigen Regulation Of Innate Immune Response Golgi Vesicle Transport Antigen Processing And Presentation Positive Regulation Of Cell Activation Positive Regulation Of Secretion
Tagcloud ?		adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?		adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?