GGA1 and CDKL3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GGA1	CDKL3
Gene Name		golgi-associated, gamma adaptin ear containing, ARF binding protein 1	cyclin-dependent kinase-like 3
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Endosome Membrane Membrane Clathrin Adaptor Complex Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Positive Regulation Of Protein Catabolic Process	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: AFTPH AP1AR APP ARF1 ARF3 ARF5 ARF6 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB F8 GGA2 GGA3 IGF2R LRP3 M6PR RAB5A RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TSG101 UBC VPS18	17 interactors: APP ATG4A CCDC155 FXR2 GGA1 GOLGA2 KRTAP10-9 LZTS2 MDFI MTUS2 PIH1D3 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A
Entrez ID		26088	51265
HPRD ID		12078	09766
Ensembl ID		ENSG00000100083	ENSG00000006837
Uniprot IDs		Q6IC75 Q9UJY5	B4DX41 E7ET86 Q8IVW4
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W	3ZDU
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Transport Protein Transport Establishment Of Protein Localization Endocytosis Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Post-Golgi Vesicle-mediated Transport Endosomal Transport Viral Protein Processing Receptor-mediated Endocytosis Regulation Of Vesicle-mediated Transport Protein Processing Regulation Of Cellular Component Organization Cellular Protein Localization Golgi Vesicle Transport Negative Regulation Of Protein Metabolic Process Intracellular Protein Transport Virion Assembly Apoptotic Process Programmed Cell Death Intracellular Transport Of Virus Cell Death Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Membrane Organization Regulation Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Proteolysis Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Lysosomal Transport Positive Regulation Of Proteolysis Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Viral Process Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Growth Regulation Of Endocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Life Cycle Positive Regulation Of Cell Cycle Arrest	MRNA Processing MRNA Metabolic Process Cellular Localization RNA Processing Regulation Of Binding Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Regulation Of Gene Expression Reproductive Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Viral Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus Sexual Reproduction RNA Splicing Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Pharynx Development Regulation Of MRNA Processing Negative Regulation Of Binding Intracellular Transport Regulation Of RNA Splicing RNA Metabolic Process Collateral Sprouting In Absence Of Injury Protein Delipidation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Reproduction Spermatogenesis Male Gamete Generation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Regulation Of Protein Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Soft Palate Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Regulation Of Metabolic Process
Tagcloud ?		adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby	10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Difference) ?		adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically rabep1 reach sense tgn traffic trafficking transmembrane tubular whereby	10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Intersection) ?