SNCA and PARK2

  • Number of citations of the paper that reports this interaction (PMID 12670421)
  • 63
  • Data Source:
  • BioGRID (affinity chromatography technology, genetic interference, genetic interference)
  • HPRD (in vivo)

SNCA

PARK2

Gene Name synuclein, alpha (non A4 component of amyloid precursor) parkin RBR E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 110 interactors: A1BG ACTA1 ADAP2 ADRBK1 AKT1 ANXA6 APLP1 APP ARHGAP15 ARPP19 BAD BAG5 BAX BCL2L1 BDH2 CALM1 CAV1 CDC42EP2 CDC42EP3 CDC42SE1 CDK4 COL25A1 COX1 COX3 CRYAB CSNK1A1 CSNK1D CSNK2A1 CSNK2A2 CTNND1 CYCS DMTN DOCK7 DYNC1H1 DYRK1A EEF1A1 EIF3G ELK1 ENC1 ENSA FGR FKBP4 FYN GABARAPL1 GAPDH GRK1 GRK5 GRK6 GSK3B HSD17B4 HSP90AA1 HSPA1A HSPA8 HSPB1 HSPB2 HSPB6 HSPB8 IARS KIAA1191 KLC1 KLK6 LYN MAP1B MAPK1 MAPK8IP1 MAPT MEF2D NEDD4 NEDD4L PAK3 PARK2 PDE4DIP PELP1 PFDN2 PINK1 PLCB2 PLD1 PLK1 PLK2 PLK3 PRDX1 PRKCE PTK2B RABAC1 RNF10 SAP30BP SDF4 SEPT4 SIAH1 SIAH2 SLC6A3 SNCAIP SNCB SPTBN1 SQSTM1 SRC SRI SUMO2 SYK SYN1 TGM1 TH TOR1A TUBA1A UBB UBC USP47 YWHAB YWHAE YWHAH 77 interactors: AIMP2 ARR3 ARRB2 ATXN3 BAG5 CASK CASP1 CASP8 CDK5 CHPF CRX CSNK1A1 CUL1 DLG1 DLX2 DNM1L DYT10 EPS15 FAM46C FBP1 FBXO7 FBXW7 GPR37 GRIN2B HEXDC IKBKG MEOX1 MEOX2 MFN1 NDUFA4L2 PAFAH1B2 PDCD2 PICK1 PRKACA PSMA1 PSMA7 PSMC5 PSMD4 RAC1 RAD1 RAD23A RANBP2 RBCK1 REL RGS2 RGS3 SEPT4 SEPT5 SIM2 SNCA SNCAIP STUB1 SYT11 TCF4 TOMM40 TOMM70A TRIP13 TUBA4A TUBB UBASH3A UBASH3B UBB UBC UBE2D2 UBE2D3 UBE2E1 UBE2G1 UBE2G2 UBE2J1 UBE2L3 UBE2L6 UBE2M UBE2N UBE2V1 UCHL1 YWHAH ZNF746
Entrez ID 6622 5071
HPRD ID 01227 03967
Ensembl ID ENSG00000145335 ENSG00000185345
Uniprot IDs H6UYS0 H6UYS5 P37840 O60260 Q5VVX4
PDB IDs 1XQ8 2JN5 2KKW 2M55 2X6M 3Q25 3Q26 3Q27 3Q28 3Q29 1IYF 2JMO 4BM9 4I1F 4I1H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2de  angustifolia  apoa1  atp5a1  atp5a1were  bioinformatics  caliber  david  diminishing  dysregulated  histopathology  hspa5  kegg  la  lavandula  lavender  le  likewise  ontology  operate  pharmaceutically  prdx2  predictedinteractions  scrutinized  searching  slowing  string  sum  tof 
ataxin  atp13a2  atxn3  b12  cag  cgg  chediak  coexist  cytopathies  fmr1  fragile  gaucher  gba  glucocerebrosidase  hereditary  higashi  idiopathic  joseph  kufor  levodopa  lyst  machado  parkin  parkinsonism  pn  polg1  premutation  rakeb  tremor 
Tagcloud (Difference) ?
2de  angustifolia  apoa1  atp5a1  atp5a1were  bioinformatics  caliber  david  diminishing  dysregulated  histopathology  hspa5  kegg  la  lavandula  lavender  le  likewise  ontology  operate  pharmaceutically  prdx2  predictedinteractions  scrutinized  searching  slowing  string  sum  tof 
ataxin  atp13a2  atxn3  b12  cag  cgg  chediak  coexist  cytopathies  fmr1  fragile  gaucher  gba  glucocerebrosidase  hereditary  higashi  idiopathic  joseph  kufor  levodopa  lyst  machado  parkin  parkinsonism  pn  polg1  premutation  rakeb  tremor 
Tagcloud (Intersection) ?