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SLC22A5 and SLC9A3R2
Number of citations of the paper that reports this interaction (PMID
15553237
)
5
Data Source:
HPRD
(two hybrid)
SLC22A5
SLC9A3R2
Gene Name
solute carrier family 22 (organic cation/carnitine transporter), member 5
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Brush Border Membrane
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Focal Adhesion
Endomembrane System
Apical Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
ATP Binding
Carnitine Transmembrane Transporter Activity
Drug Transmembrane Transporter Activity
Symporter Activity
Quaternary Ammonium Group Transmembrane Transporter Activity
PDZ Domain Binding
Antibiotic Transporter Activity
Receptor Binding
Protein Binding
Beta-catenin Binding
Protein C-terminus Binding
Phosphatase Binding
Biological Process
Sodium Ion Transport
Drug Transmembrane Transport
Quaternary Ammonium Group Transport
Carnitine Transport
Drug Transport
Antibiotic Transport
Quorum Sensing Involved In Interaction With Host
Transmembrane Transport
Positive Regulation Of Intestinal Epithelial Structure Maintenance
Sodium-dependent Organic Cation Transport
Carnitine Transmembrane Transport
Protein Complex Assembly
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways
Organic cation transport
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Organic cation/anion/zwitterion transport
SLC-mediated transmembrane transport
Drugs
L-Carnitine
Diseases
GWAS
Asthma (
20860503
)
Crohn's disease (
21102463
)
Fibrinogen (
20031577
)
Height (
20881960
)
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
4 interactors:
PDZD3
PDZK1
SLC9A3R1
SLC9A3R2
35 interactors:
ABCC4
ACTN4
ADORA2B
ADRB2
ATP2B2
CFTR
EZR
KCNJ1
LPAR1
LPAR2
P2RY1
PDPK1
PDZK1
PIK3CA
PLCB3
PODXL
PRKACA
PTEN
PTH1R
RDX
SGK1
SGK3
SIAH1
SLC22A4
SLC22A5
SLC22A9
SLC26A3
SLC34A1
SLC9A3
SLCO1A2
SLCO3A1
SRY
TAZ
TBC1D10A
WWTR1
Entrez ID
6584
9351
HPRD ID
04539
05946
Ensembl ID
ENSG00000197375
ENSG00000065054
Uniprot IDs
O76082
Q15599
PDB IDs
2D11
2HE4
2OCS
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of CGMP Biosynthetic Process
Renal Phosphate Ion Absorption
Negative Regulation Of Guanylate Cyclase Activity
Monocarboxylic Acid Transport
Glutathione Transport
Negative Regulation Of Sodium:proton Antiporter Activity
Renal Sodium Ion Transport
Cellular Phosphate Ion Homeostasis
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Sodium:proton Antiporter Activity
Carboxylic Acid Transport
Organic Acid Transport
Negative Regulation Of Sodium Ion Transmembrane Transport
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Ion Transport
Bile Acid Secretion
CGMP-mediated Signaling
Receptor Guanylyl Cyclase Signaling Pathway
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Ion Transmembrane Transport
Oligopeptide Transport
Carnitine Transport
Organic Anion Transport
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Renal Absorption
Regulation Of Proton Transport
Phosphate Ion Homeostasis
Microvillus Assembly
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Microvillus Organization
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Quaternary Ammonium Group Transport
Regulation Of CGMP Biosynthetic Process
Negative Regulation Of Lyase Activity
Regulation Of Ion Transport
Regulation Of Excretion
Monovalent Inorganic Cation Transport
Anion Transport
Regulation Of Sodium Ion Transmembrane Transporter Activity
Cyclic-nucleotide-mediated Signaling
Bile Acid And Bile Salt Transport
Regulation Of CGMP Metabolic Process
Positive Regulation Of Protein Targeting To Membrane
Dopamine Receptor Signaling Pathway
Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Nucleotide Metabolic Process
Regulation Of Protein Kinase Activity
Ion Homeostasis
Transmembrane Transport
Regulation Of Kinase Activity
Regulation Of Ion Transport
Positive Regulation Of Ion Transport
Regulation Of Protein Phosphorylation
Homeostatic Process
Positive Regulation Of Transport
Ion Transport
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Transferase Activity
Regulation Of Phosphorylation
Ion Transmembrane Transport
Cellular Cation Homeostasis
Organic Anion Transport
Cellular Ion Homeostasis
Cytosolic Calcium Ion Homeostasis
Chemical Homeostasis
Positive Regulation Of Protein Kinase Activity
Blood Circulation
Positive Regulation Of Cellular Protein Metabolic Process
Anion Transport
Platelet Activation
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Modification Process
Transport
Positive Regulation Of Protein Phosphorylation
Sodium-independent Organic Anion Transport
Carnitine Transport
Cellular Chemical Homeostasis
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Body Fluid Levels
Monocarboxylic Acid Transport
Sperm Capacitation
Anion Transmembrane Transport
Regulation Of Cellular Component Organization
Sodium Ion Transport
Inorganic Anion Transport
Regulation Of Cellular Protein Metabolic Process
Response To Organonitrogen Compound
Regulation Of Ion Transmembrane Transport
Blood Coagulation
Hemostasis
Activation Of Protein Kinase Activity
Positive Regulation Of Phosphorylation
Quaternary Ammonium Group Transport
Positive Regulation Of Cytosolic Calcium Ion Concentration
Tagcloud
?
abstracted
alleles
c113y
cardiomyopathy
carnitine
compound
confirm
corresponding
deficiency
detect
frequently
genomic
heterozygous
homozygous
missense
mutated
mutation
mutations
nonsense
parents
pcd
polyphen
predict
r254x
r289x
sanger
sequencing
sift
throughput
Tagcloud (Difference)
?
abstracted
alleles
c113y
cardiomyopathy
carnitine
compound
confirm
corresponding
deficiency
detect
frequently
genomic
heterozygous
homozygous
missense
mutated
mutation
mutations
nonsense
parents
pcd
polyphen
predict
r254x
r289x
sanger
sequencing
sift
throughput
Tagcloud (Intersection)
?