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SLC9A3 and SLC9A3R2
Number of citations of the paper that reports this interaction (PMID
9748260
)
62
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
SLC9A3
SLC9A3R2
Gene Name
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Brush Border
Cell Surface
Integral Component Of Membrane
Apical Plasma Membrane
Brush Border Membrane
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Focal Adhesion
Endomembrane System
Apical Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Sodium:proton Antiporter Activity
PDZ Domain Binding
Receptor Binding
Protein Binding
Beta-catenin Binding
Protein C-terminus Binding
Phosphatase Binding
Biological Process
Ion Transport
Regulation Of PH
Sodium Ion Transmembrane Transport
Transmembrane Transport
Hydrogen Ion Transmembrane Transport
Protein Complex Assembly
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways
Sodium/Proton exchangers
Transport of inorganic cations/anions and amino acids/oligopeptides
SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Ulcerative colitis (
23128233
)
Protein-Protein Interactions
8 interactors:
CHP1
CHP2
LRP2
MAST2
PDZK1
SHANK2
SLC9A3R1
SLC9A3R2
35 interactors:
ABCC4
ACTN4
ADORA2B
ADRB2
ATP2B2
CFTR
EZR
KCNJ1
LPAR1
LPAR2
P2RY1
PDPK1
PDZK1
PIK3CA
PLCB3
PODXL
PRKACA
PTEN
PTH1R
RDX
SGK1
SGK3
SIAH1
SLC22A4
SLC22A5
SLC22A9
SLC26A3
SLC34A1
SLC9A3
SLCO1A2
SLCO3A1
SRY
TAZ
TBC1D10A
WWTR1
Entrez ID
6550
9351
HPRD ID
01660
05946
Ensembl ID
ENSG00000066230
ENSG00000065054
Uniprot IDs
P48764
Q15599
PDB IDs
2D11
2HE4
2OCS
Enriched GO Terms of Interacting Partners
?
Regulation Of Sodium:proton Antiporter Activity
Regulation Of Calcineurin-NFAT Signaling Cascade
Regulation Of Proton Transport
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Intracellular Protein Transport
Regulation Of Sodium Ion Transmembrane Transporter Activity
Positive Regulation Of Protein Targeting To Membrane
Positive Regulation Of Intracellular Transport
Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Intracellular Protein Transport
Regulation Of Calcium-mediated Signaling
Positive Regulation Of Protein Transport
Regulation Of Sodium Ion Transport
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transport
Regulation Of Intracellular Transport
Renal Phosphate Ion Absorption
Negative Regulation Of Signaling
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Phosphatase Activity
Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Sodium:proton Antiporter Activity
Glutathione Transport
Regulation Of Dephosphorylation
Monocarboxylic Acid Transport
Regulation Of Protein Transport
Regulation Of Ion Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Monovalent Inorganic Cation Transport
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Sodium:proton Antiporter Activity
Positive Regulation Of Protein Glycosylation
Regulation Of Protein Import Into Nucleus
Positive Regulation Of Transport
Regulation Of Signaling
Renal Sodium Ion Transport
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Localization
Regulation Of Protein Localization To Nucleus
Cellular Phosphate Ion Homeostasis
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Positive Regulation Of Ion Transport
Cellular Component Assembly
Regulation Of Nucleocytoplasmic Transport
Negative Regulation Of Sodium Ion Transmembrane Transport
Protein Localization
Regulation Of Protein Kinase Activity
Ion Homeostasis
Transmembrane Transport
Regulation Of Kinase Activity
Regulation Of Ion Transport
Positive Regulation Of Ion Transport
Regulation Of Protein Phosphorylation
Homeostatic Process
Positive Regulation Of Transport
Ion Transport
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Transferase Activity
Regulation Of Phosphorylation
Ion Transmembrane Transport
Cellular Cation Homeostasis
Organic Anion Transport
Cellular Ion Homeostasis
Cytosolic Calcium Ion Homeostasis
Chemical Homeostasis
Positive Regulation Of Protein Kinase Activity
Blood Circulation
Positive Regulation Of Cellular Protein Metabolic Process
Anion Transport
Platelet Activation
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Modification Process
Transport
Positive Regulation Of Protein Phosphorylation
Sodium-independent Organic Anion Transport
Carnitine Transport
Cellular Chemical Homeostasis
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Body Fluid Levels
Monocarboxylic Acid Transport
Sperm Capacitation
Anion Transmembrane Transport
Regulation Of Cellular Component Organization
Sodium Ion Transport
Inorganic Anion Transport
Regulation Of Cellular Protein Metabolic Process
Response To Organonitrogen Compound
Regulation Of Ion Transmembrane Transport
Blood Coagulation
Hemostasis
Activation Of Protein Kinase Activity
Positive Regulation Of Phosphorylation
Quaternary Ammonium Group Transport
Positive Regulation Of Cytosolic Calcium Ion Concentration
Tagcloud
?
1p11
1q42
allows
approximate
assigned
candidate
centromere
chr
chromosomes
comparative
cytogenetic
deduce
encoding
exchanger
expand
integrates
linkage
localizations
localized
loci
map
mapping
na
orient
position
rat
regionally
respect
unlikely
Tagcloud (Difference)
?
1p11
1q42
allows
approximate
assigned
candidate
centromere
chr
chromosomes
comparative
cytogenetic
deduce
encoding
exchanger
expand
integrates
linkage
localizations
localized
loci
map
mapping
na
orient
position
rat
regionally
respect
unlikely
Tagcloud (Intersection)
?