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KLC2 and S100A8
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
KLC2
S100A8
Gene Name
kinesin light chain 2
S100 calcium binding protein A8
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Kinesin Complex
Microtubule
Membrane
Kinesin I Complex
Ciliary Rootlet
Neuron Projection
Protein Complex
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Microtubule Motor Activity
Protein Binding
Kinesin Binding
Calcium Ion Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Toll-like Receptor 4 Binding
Arachidonic Acid Binding
RAGE Receptor Binding
Biological Process
Microtubule-based Movement
Blood Coagulation
Axon Cargo Transport
Metabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cytokine Production
Leukocyte Migration Involved In Inflammatory Response
Acute Inflammatory Response
Chronic Inflammatory Response
Positive Regulation Of Peptide Secretion
Autophagy
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Response To Zinc Ion
Positive Regulation Of Cell Growth
Neutrophil Chemotaxis
Sequestering Of Zinc Ion
Response To Lipopolysaccharide
Chemokine Production
Wound Healing
Defense Response To Bacterium
Innate Immune Response
Response To Ethanol
Positive Regulation Of Inflammatory Response
Defense Response To Fungus
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytoskeleton Organization
Neutrophil Aggregation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
MHC class II antigen presentation
Kinesins
Factors involved in megakaryocyte development and platelet production
Adaptive Immune System
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-Protein Interactions
12 interactors:
AIMP2
APP
CLSTN1
COIL
KIF2A
KLC1
MAPK8IP3
PIK3R3
S100A8
YWHAG
YWHAQ
YWHAZ
18 interactors:
APP
C14orf1
CDKN1A
CEACAM3
CHGB
GDF9
IGSF21
KLC2
LRIF1
NCF2
PDCD11
PPIA
PRMT1
RAB17
S100A9
TP53
TUBA4A
UNC119
Entrez ID
64837
6279
HPRD ID
13917
00471
Ensembl ID
ENSG00000174996
ENSG00000143546
Uniprot IDs
Q9H0B6
P05109
PDB IDs
3CEQ
3EDT
1MR8
1XK4
4GGF
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Apoptotic Process
Programmed Cell Death
Positive Regulation Of Mitochondrion Organization
Cell Death
Death
Wound Healing
Response To Wounding
Regulation Of Mitochondrion Organization
Blood Coagulation
Hemostasis
Intrinsic Apoptotic Signaling Pathway
Regulation Of Body Fluid Levels
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Transport
Positive Regulation Of Transport
Axon Cargo Transport
Movement Of Cell Or Subcellular Component
Regulation Of Kinase Activity
Microtubule-based Movement
Intracellular Transport
Apoptotic Signaling Pathway
Intracellular Protein Transport
Regulation Of Organelle Organization
Regulation Of Signal Transduction
Positive Regulation Of Organelle Organization
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Protein Targeting
Regulation Of Intracellular Transport
Neutrophil Aggregation
Synaptic Growth At Neuromuscular Junction
Stress Granule Disassembly
Protein Localization
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Signaling
Establishment Of Localization In Cell
Collateral Sprouting In Absence Of Injury
Microtubule-based Transport
Regulation Of Neuron Differentiation
Positive Regulation Of Protein Metabolic Process
Immune System Process
Blood Coagulation
Hemostasis
Platelet Degranulation
Immune System Process
Stress-induced Premature Senescence
Regulation Of Body Fluid Levels
Wound Healing
Regulation Of Growth
Mitotic Cell Cycle Arrest
Positive Regulation Of Cellular Protein Metabolic Process
Response To Light Stimulus
Response To Wounding
Regulation Of Cell Growth
Positive Regulation Of Protein Metabolic Process
Immune Response
Negative Regulation Of Cell Growth
Response To Radiation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Response To X-ray
Cellular Senescence
Response To Hyperoxia
Platelet Activation
Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Mitotic Cell Cycle Phase Transition
Ras Protein Signal Transduction
Positive Regulation Of Cell Cycle Process
Regulation Of Protein Phosphorylation
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Cell Cycle Phase Transition
Response To Stimulus
Response To Abiotic Stimulus
Positive Regulation Of Programmed Cell Death
Axon Cargo Transport
Negative Regulation Of Growth
Response To Stress
Positive Regulation Of Cell Death
Response To External Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Neuron Apoptotic Process
Cellular Response To Ionizing Radiation
Signal Transduction Involved In DNA Damage Checkpoint
Positive Regulation Of Neuron Apoptotic Process
Signal Transduction Involved In Cell Cycle Checkpoint
Cellular Response To UV
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Cell Cycle
Negative Regulation Of Clathrin-mediated Endocytosis
Uncoating Of Virus
Mitotic Cell Cycle Process
Tagcloud
?
a9
auscan
australian
canadian
erythrocyte
esr
exploratory
grades
hand
hip
inverse
joint
kellgren
knee
lawrence
mcmaster
narrowing
oa
ontario
osteoarthritis
osteophytes
sedimentation
space
stiffness
structural
sum
synovial
universities
womac
Tagcloud (Difference)
?
a9
auscan
australian
canadian
erythrocyte
esr
exploratory
grades
hand
hip
inverse
joint
kellgren
knee
lawrence
mcmaster
narrowing
oa
ontario
osteoarthritis
osteophytes
sedimentation
space
stiffness
structural
sum
synovial
universities
womac
Tagcloud (Intersection)
?