KLC2 and CLSTN1

Number of citations of the paper that reports this interaction (PMID 17332754)
37

Data Source:
HPRD (in vivo, two hybrid)

		KLC2	CLSTN1
Gene Name		kinesin light chain 2	calsyntenin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Kinesin I Complex Ciliary Rootlet Neuron Projection Protein Complex	Golgi Membrane Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Junction Cell Projection Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding Kinesin Binding	Beta-amyloid Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	Microtubule-based Movement Blood Coagulation Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways		MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		12 interactors: AIMP2 APP CLSTN1 COIL KIF2A KLC1 MAPK8IP3 PIK3R3 S100A8 YWHAG YWHAQ YWHAZ	14 interactors: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		64837	22883
HPRD ID		13917	10837
Ensembl ID		ENSG00000174996	ENSG00000171603
Uniprot IDs		Q9H0B6	B3KMD3 B4E3Q1 O94985
PDB IDs		3CEQ 3EDT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Positive Regulation Of Mitochondrion Organization Cell Death Death Wound Healing Response To Wounding Regulation Of Mitochondrion Organization Blood Coagulation Hemostasis Intrinsic Apoptotic Signaling Pathway Regulation Of Body Fluid Levels Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Axon Cargo Transport Movement Of Cell Or Subcellular Component Regulation Of Kinase Activity Microtubule-based Movement Intracellular Transport Apoptotic Signaling Pathway Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Signal Transduction Positive Regulation Of Organelle Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Targeting Regulation Of Intracellular Transport Neutrophil Aggregation Synaptic Growth At Neuromuscular Junction Stress Granule Disassembly Protein Localization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Establishment Of Localization In Cell Collateral Sprouting In Absence Of Injury Microtubule-based Transport Regulation Of Neuron Differentiation Positive Regulation Of Protein Metabolic Process Immune System Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Response To DNA Damage Stimulus Response To Stress Antigen Processing And Presentation Of Peptide Antigen Axon Cargo Transport Peptidyl-lysine Modification Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Regulation Of DNA Repair Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Thymidylate Synthase Biosynthetic Process Microtubule-based Movement Movement Of Cell Or Subcellular Component Cellular Response To DNA Damage Stimulus Stress Granule Disassembly Negative Regulation Of Protein Metabolic Process Blood Coagulation Negative Regulation Of Histone H2A K63-linked Ubiquitination Hemostasis Negative Regulation Of Cell Cycle Response To Radiation Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cell Cycle Process Microtubule-based Transport DNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Response To Vitamin B1 Response To Ether Cell Cycle Arrest Cellular Component Assembly Cellular Response To Copper Ion Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair Negative Regulation Of Calcium-mediated Signaling Regulation Of Body Fluid Levels Behavior Protein Localization To Nucleus Negative Regulation Of DNA Repair DNA Repair Chromatin Modification Wound Healing Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-17 Production Histone H3-K9 Trimethylation
Tagcloud ?			adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Difference) ?			adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Intersection) ?