RUSF1 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RUSF1	PGRMC2
Description		RUS family member 1	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region Nucleus Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Endomembrane System Membrane Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process		Heme Transport Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Adipose Tissue Development
Pathways			RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Heme signaling
Drugs
Diseases
GWAS			Bone mineral density (total hip) ( 29883787)
Interacting Genes		53 interacting genes: AQP6 ARL13B ARL6IP6 BIK C5orf46 CISD2 CMTM5 CREB3 CREB3L1 CREB3L3 DGAT2L6 DHRSX EBP EHHADH ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GJA8 GPR42 HSD17B13 IFNGR1 IL10RA ITGAM LHFPL5 LMNA MMGT1 MS4A4A ODF4 PDCD1LG2 PGRMC2 PSCA PVR RETREG3 RNF5 SCN3B SFXN3 SLC10A1 SLC10A6 SLC30A8 SLC35E3 SLC35H1 SPAG4 SSMEM1 TEX29 TMEM237 TMEM248 TMEM35A TMX2 UBE2I ZCCHC12 ZDHHC15	55 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LINC00632 LPAR3 MALL MFHAS1 ORMDL1 PEDS1-UBE2V1 PEX16 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		64755	10424
HPRD ID		07839	09665
Ensembl ID		ENSG00000140688	ENSG00000164040
Uniprot IDs		Q96GQ5	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Protein Binding Positive Regulation Of Acute Inflammatory Response Endoplasmic Reticulum Membrane Bile Acid:sodium Symporter Activity Acetylcholine Receptor Regulator Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Myelination Axon Ensheathment Alkenylglycerophosphocholine Hydrolase Activity Compact Myelin
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