RUSF1 and PDCD1LG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RUSF1	PDCD1LG2
Description		RUS family member 1	programmed cell death 1 ligand 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Adaptive Immune Response Immune System Process Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Type II Interferon Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways			Co-inhibition by PD-1 PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		53 interacting genes: AQP6 ARL13B ARL6IP6 BIK C5orf46 CISD2 CMTM5 CREB3 CREB3L1 CREB3L3 DGAT2L6 DHRSX EBP EHHADH ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GJA8 GPR42 HSD17B13 IFNGR1 IL10RA ITGAM LHFPL5 LMNA MMGT1 MS4A4A ODF4 PDCD1LG2 PGRMC2 PSCA PVR RETREG3 RNF5 SCN3B SFXN3 SLC10A1 SLC10A6 SLC30A8 SLC35E3 SLC35H1 SPAG4 SSMEM1 TEX29 TMEM237 TMEM248 TMEM35A TMX2 UBE2I ZCCHC12 ZDHHC15	20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35H1 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97
Entrez ID		64755	80380
HPRD ID		07839	16147
Ensembl ID		ENSG00000140688	ENSG00000197646
Uniprot IDs		Q96GQ5	Q9BQ51
PDB IDs			6UMT 8J3V
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Protein Binding Positive Regulation Of Acute Inflammatory Response Endoplasmic Reticulum Membrane Bile Acid:sodium Symporter Activity Acetylcholine Receptor Regulator Activity	Membrane Glutamine Transport L-glutamine Transmembrane Transporter Activity Amino Acid Transmembrane Transport Amino Acid Transport
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