GORASP1 and TRAF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GORASP1	TRAF4
Description		golgi reassembly stacking protein 1	TNF receptor associated factor 4
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Membrane Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	Protein Binding Metal Ion Binding	Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Transferase Activity Enzyme Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Signaling Adaptor Activity Identical Protein Binding Metal Ion Binding WW Domain Binding
	Biological Process	Protein N-linked Glycosylation Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Plasma Membrane Golgi Ribbon Formation	Immune System Process Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Respiratory Tube Development Regulation Of Apoptotic Process Regulation Of Canonical NF-kappaB Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Social communication problems ( 24564958)
Interacting Genes		17 interacting genes: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 NEFL PLK1 PRKD2 RPS6KA1 SCRN1 TGFA TMED2 TMED3 TRAF4	137 interacting genes: ABI3 ACTMAP ALKBH4 ANXA1 AR ATOSB ATOX1 BACH2 BAHD1 BANP BCKDK BCL6B BEGAIN BEX3 BYSL CALCOCO2 CAV1 CBL CBLC CCHCR1 CENPE CEP85 CHEK1 CHUK DISC1 DNM2 DPEP2NB DTX3 EXOC7 EYA2 EZHIP FAM90A1 FAT1 FBXL18 FRS3 FTH1 GOLGA2 GOLGA6A GOLGA6L9 GORASP1 GORASP2 GPRASP1 HEY2 HGS HMG20A HOMEZ HOXA1 HOXB5 IRAK1 IRS1 ISYNA1 KANK2 KANSL1 KDM1A KRT31 KRT36 LENG8 LNX1 LTBR MAGEC2 MAGED1 MAP3K4 MRPL28 NCF1 NGFR NHERF2 NOS1AP NPAS2 NTRK1 NUDT16L1 OGT PCSK5 PDE4DIP PHLDA1 PICK1 PKD1P1 PLAGL2 PLEKHA7 PLSCR1 POLR2J POLR2J3 PSMC3 QARS1 RAD54L2 RBPMS REXO1L6P RNF114 RNF144B RNF4 RPS6KB1 SF3B4 SIGLEC7 SMURF1 SMURF2 SNRPB SORBS2 SPDL1 SUMO1 TARBP2 TAX1BP1 TBC1D7 TBC1D8 TFAP4 TGFB1I1 TICAM1 TNFRSF4 TP53BP2 TRAF6 TRIM27 TRIM37 TSGA10IP TYK2 UBC UBE2D1 UBE2I UBL4A UBL4B USP7 VPS52 WBP11 WWP1 WWP2 ZBTB16 ZBTB26 ZC3H12C ZMYM5 ZNF177 ZNF275 ZNF3 ZNF512B ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF784 ZNF835 ZRANB1
Entrez ID		64689	9618
HPRD ID		06038	03915
Ensembl ID		ENSG00000114745	ENSG00000076604
Uniprot IDs		A0A8Q3SHU6 A0A8Q3WL08 B3KPY8 B4E1H8 Q9BQQ3	Q9BUZ4
PDB IDs		4REY 6G8T 6G8W	2EOD 2YUC 3ZJB 4K8U 4M4E 5YC1
Enriched GO Terms of Interacting Partners?		Protein Serine Kinase Activity Golgi Organization Protein Phosphorylation Phosphorylation Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Cycle Protein Kinase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Kinase Activity Protein Modification Process Cellular Response To Staurosporine COPII-coated ER To Golgi Transport Vesicle Regulation Of Apoptotic Process Golgi Disassembly Regulation Of Programmed Cell Death Centrosome Cycle Hepatocyte Proliferation G2/M Transition Of Mitotic Cell Cycle Protein Metabolic Process Cell Cycle G2/M Phase Transition Potassium Channel Inhibitor Activity Golgi Cisterna Membrane Fibroblast Apoptotic Process Mitotic Nuclear Membrane Disassembly Transferase Activity Intracellular Signal Transduction Nuclear Membrane Disassembly Microtubule Organizing Center Organization Membrane Disassembly COPI-coated Vesicle Membrane Protein Kinase Binding Cytoplasm Protein Poly-ADP-ribosylation Aspartic-type Endopeptidase Activity Neuron Apoptotic Process Peptidyl-threonine Phosphorylation Execution Phase Of Apoptosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Localization To Site Of Double-strand Break Microtubule Cytoskeleton Organization Involved In Mitosis Apoptotic Process Programmed Cell Death Cell Death Mitotic Cell Cycle Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Phosphate-containing Compound Metabolic Process Cellular Response To Alkaloid ATP Binding Chromosome Condensation Cell Cycle Phase Transition	Protein Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Cytosol Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Transcription By RNA Polymerase II Ubiquitin-protein Transferase Activity Regulation Of Gene Expression Ubiquitin Protein Ligase Activity Post-translational Protein Modification Negative Regulation Of RNA Metabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cell Surface Toll-like Receptor Signaling Pathway Identical Protein Binding Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Proteolysis Involved In Protein Catabolic Process Cytoplasm Positive Regulation Of Metabolic Process Regulation Of Protein Modification Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Regulation Of Protein Ubiquitination PML Body Regulation Of Programmed Cell Death Negative Regulation Of Macromolecule Biosynthetic Process Signaling Adaptor Activity Zinc Ion Binding Proteolysis Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Catabolic Process Positive Regulation Of Protein Metabolic Process
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