GORASP1 and AGPS

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid, two hybrid)

		GORASP1	AGPS
Name		golgi reassembly stacking protein 1	alkylglycerone phosphate synthase
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Protein N-linked Glycosylation Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Plasma Membrane Golgi Ribbon Formation	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport	Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Diseases		None	Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Social communication problems ( 24564958 )	Height ( 28552196 )
Novel Interactors		4 novel interactors: BSN CLEC3B ENSA OXSR1	12 novel interactors: BLVRA BOLL CHRND CS FKBP7 GORASP2 KCNH7 KEL LST1 NFIA PDE11A TSFM
Interacting Genes		17 interacting genes: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 NEFL PLK1 PRKD2 RPS6KA1 SCRN1 TGFA TMED2 TMED3 TRAF4	2 interacting genes: GNPAT GORASP1
Entrez ID		64689	8540
HPRD ID		06038	04337
Ensembl ID		ENSG00000114745	ENSG00000018510
Uniprot IDs		A0A8Q3SHU6 A0A8Q3WL08 B3KPY8 B4E1H8 Q9BQQ3	B7Z3Q4 O00116
PDB IDs		4REY 6G8T 6G8W	Not available
GO Terms Enriched among Interactors		Protein Serine Kinase Activity Golgi Organization Protein Phosphorylation Phosphorylation Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Cycle Protein Kinase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Kinase Activity Protein Modification Process Cellular Response To Staurosporine COPII-coated ER To Golgi Transport Vesicle Regulation Of Apoptotic Process Golgi Disassembly Regulation Of Programmed Cell Death Centrosome Cycle Hepatocyte Proliferation G2/M Transition Of Mitotic Cell Cycle Protein Metabolic Process Cell Cycle G2/M Phase Transition Potassium Channel Inhibitor Activity Golgi Cisterna Membrane Fibroblast Apoptotic Process Mitotic Nuclear Membrane Disassembly Transferase Activity Intracellular Signal Transduction Nuclear Membrane Disassembly Microtubule Organizing Center Organization Membrane Disassembly COPI-coated Vesicle Membrane Protein Kinase Binding Cytoplasm Protein Poly-ADP-ribosylation Aspartic-type Endopeptidase Activity Neuron Apoptotic Process Peptidyl-threonine Phosphorylation Execution Phase Of Apoptosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Localization To Site Of Double-strand Break Microtubule Cytoskeleton Organization Involved In Mitosis Apoptotic Process Programmed Cell Death Cell Death Mitotic Cell Cycle Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Phosphate-containing Compound Metabolic Process Cellular Response To Alkaloid ATP Binding Chromosome Condensation Cell Cycle Phase Transition	None