SH3BP2 and PDLIM7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SH3BP2	PDLIM7
Gene Name		SH3-domain binding protein 2	PDZ and LIM domain 7 (enigma)
Image
Gene Ontology Annotations	Cellular Component		Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding	Protein Binding Zinc Ion Binding
	Biological Process	Signal Transduction Positive Regulation Of Signal Transduction	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ABL1 DBNL ERBB2 FGFR1 FLT3 FYN GRB2 LAT LCK PDLIM7 PLCG1 PLCG2 SH3KBP1 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70	34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		6452	9260
HPRD ID		03657	10436
Ensembl ID		ENSG00000087266	ENSG00000196923
Uniprot IDs		D6R919 P78314	Q9NR12
PDB IDs		2CR4 3TWR	2Q3G
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Fc-epsilon Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Blood Coagulation Innate Immune Response Wound Healing Hemostasis Platelet Activation Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Cell Activation Antigen Receptor-mediated Signaling Pathway Response To Wounding Positive Regulation Of Signal Transduction Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Signal Transduction Intracellular Signal Transduction Positive Regulation Of Immune Response Endocytosis Neurotrophin TRK Receptor Signaling Pathway Regulation Of Signaling Neurotrophin Signaling Pathway Immune Response Defense Response Immune System Process Regulation Of Lymphocyte Activation Phagocytosis Cell Migration Vesicle-mediated Transport Cell Motility Positive Regulation Of Immune System Process Regulation Of Cell Activation Locomotion Cell Surface Receptor Signaling Pathway Protein Autophosphorylation Regulation Of Intracellular Signal Transduction Leukocyte Migration Regulation Of Cell-cell Adhesion Cellular Response To Growth Factor Stimulus Response To Growth Factor Lymphocyte Activation	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		bilateral boy calcineurin candidates cherubism copyright disfigurement facial giant granuloma immunohistological intra jaw jaws multinucleated nfatc1 operative opg osseous osteoclastogenesis osteoclasts osteogenesis protected radiological rankl reserved rights stabilization tacrolimus
Tagcloud (Difference) ?		bilateral boy calcineurin candidates cherubism copyright disfigurement facial giant granuloma immunohistological intra jaw jaws multinucleated nfatc1 operative opg osseous osteoclastogenesis osteoclasts osteogenesis protected radiological rankl reserved rights stabilization tacrolimus
Tagcloud (Intersection) ?