SH3BP2

Description		SH3 domain binding protein 2
Image
GO Annotations	Cellular Component
	Molecular Function	Phosphotyrosine Residue Binding Protein Binding SH3 Domain Binding
	Biological Process	Signal Transduction
Pathways
Drugs
Diseases		Cherubism
GWAS		Hodgkin's lymphoma ( 34216518) Huntington's disease progression ( 28642124) Multiple sclerosis ( 24076602)
Novel Interacting Genes		1 novel interacting genes: NSD2
Interacting Genes		31 interacting genes: ABL1 ARHGAP10 CTTN DBNL ERBB2 ERBB3 ERBB4 FGFR1 FLT3 FYN GRB2 HCLS1 KIT LAT LCK MET MYO1F PDLIM7 PLCG1 PLCG2 SH3KBP1 SH3RF1 STAT3 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70
Entrez ID		6452
HPRD ID		03657
Ensembl ID		ENSG00000087266
Uniprot IDs		A0A384N6E5 P78314
PDB IDs		2CR4 3TWR
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Phosphotyrosine Residue Binding Intracellular Signaling Cassette Peptidyl-tyrosine Phosphorylation Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway Signal Transduction Positive Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Fc-gamma Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Immune Response-activating Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Immune System Process Regulation Of Lymphocyte Activation Fc Receptor Mediated Stimulatory Signaling Pathway Cell Activation Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Multicellular Organismal Process Activation Of Immune Response Cell Motility Plasma Membrane Cell Migration Lymphocyte Activation Regulation Of Signaling Regulation Of Cell Communication Protein Kinase Activity Regulation Of Cell Activation Positive Regulation Of Immune Response T Cell Activation Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Multicellular Organismal Process Leukocyte Activation Positive Regulation Of Lymphocyte Activation Regulation Of Immune Response Immune System Process
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