XAGE2 and GMCL2

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		XAGE2	GMCL2
Name		X antigen family member 2	germ cell-less 2, spermatogenesis associated
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	None	Nucleus Nuclear Matrix
	Molecular Function	Protein Binding	Protein Binding Cullin Family Protein Binding
	Biological Process	None	Germ Cell Development Spermatogenesis Protein Ubiquitination Cell Differentiation
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		7 interacting genes: EHMT2 EPS8 FOXP4 GMCL1 GMCL2 POT1 TERF2IP	22 interacting genes: ADAMTSL4 BCL11A BHLHE40 CHCHD3 DVL2 FBXO7 GAGE12B GAGE12I GAGE2E GAGE5 HNRNPM IKZF1 KAT5 LIMS3 LZTS2 MEOX2 SHQ1 TRAF1 TRIM23 UBE2I USHBP1 XAGE2
Entrez ID		9502	64396
HPRD ID		02332	17044
Ensembl ID		ENSG00000155622	ENSG00000244234
Uniprot IDs		Q96GT9	Q8NEA9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase Germ Cell Development RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Cellular Component Organization Negative Regulation Of Telomere Maintenance Chromosome Organization Histone H3K56 Methyltransferase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Regulation Of Organelle Organization Regulation Of DNA Metabolic Process Positive Regulation Of Telomeric Loop Disassembly Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Negative Regulation Of DNA Recombination At Telomere Phenotypic Switching 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomere Organization Nuclear Matrix Negative Regulation Of DNA Metabolic Process Adult Behavior Regulation Of Double-strand Break Repair Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Dimethylation Chromosome Single-stranded Telomeric DNA Binding Chromosome, Telomeric Region Histone H3K27 Methyltransferase Activity Actin Polymerization-dependent Cell Motility Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Protection From Non-homologous End Joining At Telomere Histone H3K9me2 Methyltransferase Activity DEAD/H-box RNA Helicase Binding NMDA Selective Glutamate Receptor Complex Behavioral Response To Ethanol	None