PCBP1 and ANP32A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PCBP1	ANP32A
Gene Name		poly(rC) binding protein 1	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Gene Expression Intracellular Signal Transduction
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS			Esophageal cancer ( 21642993)
Protein-Protein Interactions		36 interactors: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBM11 RBM42 SNRPA SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	27 interactors: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HIST4H4 HSPB3 KPNA1 KPNA5 KPNA6 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		5093	8125
HPRD ID		03128	09014
Ensembl ID		ENSG00000169564	ENSG00000140350
Uniprot IDs		Q15365 Q53SS8	P39687
PDB IDs		1WVN 1ZTG 3VKE	2JE0 2JE1
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Macromolecule Biosynthetic Process Negative Regulation Of Potassium Ion Transmembrane Transport MRNA 3'-end Processing RNA Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Ventricular Cardiac Muscle Cell Action Potential RNA 3'-end Processing Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Translation Cellular Process Cardiac Muscle Cell Action Potential Involved In Contraction Biosynthetic Process MRNA Polyadenylation Positive Regulation Of RNA Splicing Cardiac Muscle Cell Action Potential RNA Polyadenylation	DNA Replication-dependent Nucleosome Assembly Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Silencing At RDNA Nucleosome Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Assembly Negative Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Nuclear Transport Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Chromatin Silencing Negative Regulation Of Cellular Metabolic Process DNA Methylation On Cytosine Cytoplasmic Transport DNA Conformation Change Gene Expression DNA Metabolic Process Negative Regulation Of Gene Expression, Epigenetic NLS-bearing Protein Import Into Nucleus Telomere Maintenance Regulation Of Nitrogen Compound Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Cellular Macromolecular Complex Assembly Gene Silencing Regulation Of Metabolic Process Histone H4-K20 Demethylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of RNA Metabolic Process Intracellular Transport Protein Localization To Nucleus DNA Methylation Nitrogen Compound Metabolic Process Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Organelle Organization
Tagcloud ?		atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv	achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced
Tagcloud (Difference) ?		atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv	achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced
Tagcloud (Intersection) ?