PCBP1 and RBM42

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PCBP1	RBM42
Description		poly(rC) binding protein 1	RNA binding motif protein 42
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Appendicular lean mass ( 33097823) Male-pattern baldness ( 28196072)
Interacting Genes		56 interacting genes: ANP32A APP ARIH1 BCL2L13 CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HMGB2 HNRNPD HNRNPK HNRNPLL HSPA13 HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 OGT PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SIVA1 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TNFAIP3 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	23 interacting genes: APP BAG4 CEP55 DMRTB1 FHL3 HNRNPK OGT PCBP1 PPIL1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM4 RBPMS RBPMS2 SFSWAP SNRPA TRNAU1AP WBP4
Entrez ID		5093	79171
HPRD ID		03128	11303
Ensembl ID		ENSG00000169564	ENSG00000126254
Uniprot IDs		Q15365 Q53SS8	Q9BTD8
PDB IDs		1WVN 1ZTG 3VKE	6QW6 6QX9 8H6E 8H6J 8QP8 8QP9 8QPK 8QXD 8R08 8R0A
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process RNA Binding MRNA Metabolic Process RNA Processing MRNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleus MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Ribonucleoprotein Complex Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process Nucleoplasm Negative Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck MRNA Stabilization Negative Regulation Of Gene Expression MRNA 3'-UTR Binding CRD-mediated MRNA Stabilization Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Negative Regulation Of Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleic Acid Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Splicing MRNA Binding MRNA Processing RNA Binding Cytoplasmic Stress Granule MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Spliceosomal Complex Pre-mRNA Intronic Binding Regulation Of Translation Pre-mRNA Binding Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Nucleic Acid Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Post-transcriptional Regulation Of Gene Expression MiRNA Binding Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MRNA Modification Negative Regulation Of Translational Initiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Translation
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