SEMG1 and TGM1

Number of citations of the paper that reports this interaction (PMID 9523691)
10

Data Source:
HPRD (in vitro)

		SEMG1	TGM1
Gene Name		semenogelin I	transglutaminase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Secretory Granule Extracellular Vesicular Exosome	Cornified Envelope Cell-cell Adherens Junction Intrinsic Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Insemination	Cellular Protein Modification Process Organ Morphogenesis Peptide Cross-linking Keratinocyte Differentiation Keratinization Cell Envelope Organization
Pathways		Amyloids
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: KLK2 KLK3 PRKCA SEMG2 TGM1 UBQLN4	6 interactors: HSPB1 MDK RARRES3 SEMG1 SEMG2 SNCA
Entrez ID		6406	7051
HPRD ID		01641	01824
Ensembl ID		ENSG00000124233	ENSG00000092295
Uniprot IDs		P04279	P22735
PDB IDs			2XZZ
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Positive Regulation Of Inflammatory Response Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Blood Coagulation Regulation Of Wound Healing Factor XII Activation Cell Envelope Organization Histone H3-T6 Phosphorylation Positive Regulation Of Fibrinolysis Regulation Of Angiogenesis Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Inflammatory Response Plasminogen Activation Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Plasma Kallikrein-kinin Cascade Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Desmosome Organization Regulation Of Fibrinolysis Blood Coagulation, Intrinsic Pathway Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Blood Coagulation Hemostasis Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Protein Processing Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Acute Inflammatory Response Negative Regulation Of CAMP Biosynthetic Process Activation Of Adenylate Cyclase Activity Fibrinolysis Regulation Of Cardiac Muscle Hypertrophy Rhodopsin Mediated Signaling Pathway Regulation Of Platelet Activation Positive Regulation Of Positive Chemotaxis Negative Regulation Of CAMP Metabolic Process Regulation Of The Force Of Heart Contraction Inactivation Of MAPK Activity Regulation Of Body Fluid Levels Wound Healing Mitotic Nuclear Envelope Disassembly	Regulation Of Cellular Response To Oxidative Stress Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Defecation Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Neuron Apoptotic Process Regulation Of Behavior Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Cell Death Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Neuron Death Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Protein Phosphorylation Dopamine Transport Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Behavioral Response To Cocaine Short-term Memory Phospholipid Metabolic Process Regulation Of Neurotransmitter Uptake Negative Regulation Of Microtubule Polymerization Positive Regulation Of Neurotransmitter Secretion
Tagcloud ?		acids amino assisted changed computer cysteine ejaculation epididymal eppin fragment fragments glycine hydrolyzed lactotransferrin live motility originally progressive protease psa recombinant reversing semenogelin seminal sperm spermatozoa spinlw1 washed	accelerated b1 block blot cdk4 closely cycle cyclin cytometry displayed explore expressions g0 g1 g2 hacat immortalized immunocytochemistry inmmnohistochemistry interference interfering keratinocytes phases rnai silencing sirna transfecting transglutaminase western
Tagcloud (Difference) ?		acids amino assisted changed computer cysteine ejaculation epididymal eppin fragment fragments glycine hydrolyzed lactotransferrin live motility originally progressive protease psa recombinant reversing semenogelin seminal sperm spermatozoa spinlw1 washed	accelerated b1 block blot cdk4 closely cycle cyclin cytometry displayed explore expressions g0 g1 g2 hacat immortalized immunocytochemistry inmmnohistochemistry interference interfering keratinocytes phases rnai silencing sirna transfecting transglutaminase western
Tagcloud (Intersection) ?