TGM1 and SULT4A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TGM1	SULT4A1
Description		transglutaminase 1	sulfotransferase family 4A member 1
Image
GO Annotations	Cellular Component	Cornified Envelope Cytosol Plasma Membrane Membrane Extracellular Exosome	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Identical Protein Binding Metal Ion Binding	Protein Binding Sulfotransferase Activity Transferase Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Keratinocyte Differentiation Keratinization Protein Modification Process Cell Envelope Organization Positive Regulation Of Cell Cycle Animal Organ Development	Lipid Metabolic Process Sulfur Compound Metabolic Process Steroid Metabolic Process Sulfation Dendrite Arborization
Pathways		Formation of the cornified envelope	Cytosolic sulfonation of small molecules
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS			Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4	6 interacting genes: AKT1 MAPK3 POT1 PTPA RUNX1 TGM1
Entrez ID		7051	25830
HPRD ID		01824	07462
Ensembl ID		ENSG00000092295	ENSG00000130540
Uniprot IDs		P22735	B7Z2E1 Q9BR01
PDB IDs		2XZZ	1ZD1
Enriched GO Terms of Interacting Partners?		Epidermis Development Negative Regulation Of Flagellated Sperm Motility Positive Regulation Of Serine-type Endopeptidase Activity Keratinization Positive Regulation Of Endopeptidase Activity Regulation Of Locomotion Endocytosis Positive Regulation Of Peptidase Activity	Cellular Response To Amino Acid Starvation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of T Cell Activation Negative Regulation Of Cell-cell Adhesion Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of TORC1 Signaling Regulation Of Proteolysis Negative Regulation Of Cell Adhesion Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA Metabolic Process Response To Amino Acid Starvation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lipid Transport Response To Epidermal Growth Factor TORC1 Signaling Regulation Of Protein Maturation Lipopolysaccharide-mediated Signaling Pathway Phosphatase Binding Positive Regulation Of Cellular Component Organization ERBB Signaling Pathway TOR Signaling Regulation Of TRNA Methylation Insulin Receptor Signaling Pathway Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of DNA Metabolic Process Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Positive Regulation Of Organelle Organization Regulation Of Organ Growth Cellular Response To Tumor Necrosis Factor Regulation Of Cell-cell Adhesion ATP Binding Negative Regulation Of Immune System Process Regulation Of Lymphocyte Activation Negative Regulation Of Autophagy Regulation Of Cellular Response To Stress Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Protein Autophosphorylation Response To Tumor Necrosis Factor Negative Regulation Of Protein Localization To Lysosome Cell Envelope Organization Positive Regulation Of Telomeric Loop Disassembly Positive Regulation Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin-like Growth Factor Stimulus Regulation Of Cell Activation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?