Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PRDM1 and HIST1H1A
Number of citations of the paper that reports this interaction (PMID
14985713
)
87
Data Source:
BioGRID
(enzymatic study)
PRDM1
HIST1H1A
Gene Name
PR domain containing 1, with ZNF domain
histone cluster 1, H1a
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleosome
Nuclear Chromatin
Nuclear Euchromatin
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Methyltransferase Activity
Histone Deacetylase Binding
Metal Ion Binding
Protein Binding
Chromatin DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Maternal Placenta Development
Transcription, DNA-templated
Germ Cell Development
Post-embryonic Development
Positive Regulation Of Gene Expression
Negative Regulation Of B Cell Proliferation
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Methylation
Eye Photoreceptor Cell Development
Cell Fate Commitment
Positive Regulation Of B Cell Differentiation
Intestinal Epithelial Cell Development
Trophoblast Giant Cell Differentiation
Nucleosome Assembly
Spermatogenesis
Pathways
DNA Damage/Telomere Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Activation of DNA fragmentation factor
Apoptosis induced DNA fragmentation
Cellular Senescence
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) (
23648065
)
Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) (
23648065
)
Crohn's disease (
21102463
)
Systemic lupus erythematosus (
23273568
19838193
)
Protein-Protein Interactions
9 interactors:
AES
ATXN1
HIST1H1A
HIST2H3A
IRF4
KDM1A
PIAS1
TLE1
TLE2
45 interactors:
AEBP2
CCNA1
CCNA2
CCNB1
CCND2
CCNE1
CDK1
CDK2
CDK4
CDK6
CDK7
CDKN1B
CRP
CTCFL
EED
EHMT2
EP300
EZH2
GADD45A
GZMA
IRAK4
KAT2B
LIMK1
LIMK2
LOX
NAP1L4
NASP
PARP1
PARP3
PELP1
PKN1
PRDM1
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKDC
PTMA
RBBP4
SUZ12
TERF1
TERF2IP
TLK1
WHSC1L1
Entrez ID
639
3024
HPRD ID
04572
00820
Ensembl ID
ENSG00000057657
ENSG00000124610
Uniprot IDs
B4DW27
O75626
Q02539
PDB IDs
3DAL
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Negative Regulation Of Cellular Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Regulation Of Signaling
Regulation Of Anoikis
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Binding
Positive Regulation Of Gene Expression
Wnt Signaling Pathway
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Organ Development
Biosynthetic Process
Regulation Of Primitive Erythrocyte Differentiation
Positive Regulation Of Interleukin-13 Biosynthetic Process
Regulation Of DNA Binding
Negative Regulation Of Binding
Regulation Of Metabolic Process
Positive Regulation Of Interleukin-10 Biosynthetic Process
Positive Regulation Of Interleukin-4 Biosynthetic Process
Myeloid Leukocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Interferon-gamma-mediated Signaling Pathway
Notch Signaling Pathway
Response To Stimulus
Chromosome Organization
Cell Cycle
Chromatin Organization
Chromatin Modification
Regulation Of Cell Cycle
Organelle Organization
Cell Cycle Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Histone Modification
Regulation Of Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Protein Metabolic Process
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Mitotic Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Kinase Activity
Regulation Of Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Cellular Protein Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Phosphorus Metabolic Process
Protein Phosphorylation
Regulation Of Mitotic Cell Cycle
Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Cell Division
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Cycle
DNA Metabolic Process
Cellular Response To Stress
Response To Stress
Histone Phosphorylation
Regulation Of Catalytic Activity
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Regulation Of Cell Cycle Process
Phosphorylation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cell Cycle
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression, Epigenetic
Tagcloud
?
122c
2012cb944901
9qh
azoospermia
blimp1
dazl
ddx4
declare
dppa3
envisioned
fam122c
funds
grants
hef
ikbkg
ipsc
ipscs
lin28
poi
poi1
poi2
q26
rbmx
stella
sublines
talents
vasa
xq
znf
Tagcloud (Difference)
?
122c
2012cb944901
9qh
azoospermia
blimp1
dazl
ddx4
declare
dppa3
envisioned
fam122c
funds
grants
hef
ikbkg
ipsc
ipscs
lin28
poi
poi1
poi2
q26
rbmx
stella
sublines
talents
vasa
xq
znf
Tagcloud (Intersection)
?