PRDM1 and KDM1A

  • Number of citations of the paper that reports this interaction (PMID 19124609)
  • 23
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

PRDM1

KDM1A

Gene Name PR domain containing 1, with ZNF domain lysine (K)-specific demethylase 1A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Crohn's disease ( 21102463)
  • Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions 9 interactors: AES ATXN1 HIST1H1A HIST2H3A IRF4 KDM1A PIAS1 TLE1 TLE2 219 interactors: AKAP9 ANKEF1 AP1G2 AR ARHGAP15 ARHGAP29 ASB10 ASB3 ASCC2 ATP5J2 ATP6V1B1 BAHD1 BAIAP2 BATF BCAT1 BLZF1 BMP3 BRCA1 C16orf59 C17orf82 C18orf54 C4orf17 C8orf48 C8orf74 CCDC121 CCDC14 CCDC151 CCDC155 CCDC172 CCDC37 CCDC53 CCDC74A CCDC74B CCDC90B CDC23 CDC5L CDCA4 CDCA5 CENPQ CEP162 CEP70 CRBN CRLF3 CTBP1 DBF4B DNAJA3 DNTTIP1 DYX1C1 E2F1 ECI2 ELOF1 EXOC1 EZH2 FAM9A FIGNL1 FYCO1 FYN GABPB2 GDF9 GLYR1 GOLGA2 GPATCH2L GSTCD GTPBP2 H3F3C HAUS1 HAUS3 HAUS6 HDAC1 HESX1 HIST1H3A HIST2H3C HIST3H3 HOXA1 ID2 IFI35 IGFBP4 IK IKBIP IL16 IMMT INTS2 ISL1 ITGB3BP ITSN2 KANSL1 KDM5B KIAA0408 KIFC3 KLC3 KLF3 KLHDC4 KRT17 KRT19 KRT222 KRT33B KRT38 KRT6A KRT6B KRT7 L3MBTL3 LENG8 LOXL4 MALT1 MBD3 MBD4 MCPH1 MCRS1 MLC1 MNS1 MTA3 MTF2 MTMR9 MTO1 MYC MYLIP NBPF15 NDUFA8 NDUFS1 NECAB2 NEFL NF2 NMI NOSTRIN NR1H2 NR1H3 NR2C2 NR2E1 OFCC1 OIP5 OPA3 OTUB1 PDCD5 PDE4DIP PEX7 PHC2 PHF19 PHF20L1 PHF21A PMF1 PNKP PPARD PPP1R12A PRDM1 PRIM2 PSMC1 PSMC3 RASSF1 RASSF2 RASSF8 RCOR1 RCOR3 RNF10 RPRD1A SAMD3 SEPT6 SERGEF SETDB1 SF3B2 SH3GLB2 SLU7 SMAD9 SMARCD1 SMN1 SNF8 SNX15 SOCS6 SPATA22 SPATA24 SPICE1 SPRY2 SPSB1 SPZ1 SRGAP3 SSX2IP STAT3 STX11 STX19 SUMO1 SUMO2 SUV39H1 TACC1 TADA3 TAL1 TDO2 TERF1 TEX35 TEX9 TNFAIP1 TNNT2 TP53 TRAF4 TRIM39 TRIM54 TSACC TSC1 TTC33 UBA3 UCHL5 UNC119 UNKL USP28 VPS11 VPS37A WBSCR27 WDR83 YEATS4 ZBTB24 ZCCHC17 ZFP28 ZNF280A ZNF333 ZNF436 ZNF451 ZNF480 ZNF581 ZNF641 ZNF71 ZNF829
Entrez ID 639 23028
HPRD ID 04572 09800
Ensembl ID ENSG00000057657 ENSG00000004487
Uniprot IDs B4DW27 O75626 O60341
PDB IDs 3DAL 2COM 2DW4 2EJR 2H94 2HKO 2IW5 2L3D 2UXN 2UXX 2V1D 2X0L 2XAF 2XAG 2XAH 2XAJ 2XAQ 2XAS 2Y48 2Z3Y 2Z5U 3ABT 3ABU 3ZMS 3ZMT 3ZMU 3ZMV 3ZMZ 3ZN0 3ZN1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
122c  2012cb944901  9qh  azoospermia  blimp1  dazl  ddx4  declare  dppa3  envisioned  fam122c  funds  grants  hef  ikbkg  ipsc  ipscs  lin28  poi  poi1  poi2  q26  rbmx  stella  sublines  talents  vasa  xq  znf 
aml  blasts  ccaat  confers  corepressor  corest  demethylase  demethylates  depleted  di  engrafted  engraftment  exhibiting  h3k4me3  hdi  lsd1  mark  me2  mono  npm1  oncoproteins  pan  panobinostat  permissive  ps  shrna  sp2509  synergistically  warranting 
Tagcloud (Difference) ?
122c  2012cb944901  9qh  azoospermia  blimp1  dazl  ddx4  declare  dppa3  envisioned  fam122c  funds  grants  hef  ikbkg  ipsc  ipscs  lin28  poi  poi1  poi2  q26  rbmx  stella  sublines  talents  vasa  xq  znf 
aml  blasts  ccaat  confers  corepressor  corest  demethylase  demethylates  depleted  di  engrafted  engraftment  exhibiting  h3k4me3  hdi  lsd1  mark  me2  mono  npm1  oncoproteins  pan  panobinostat  permissive  ps  shrna  sp2509  synergistically  warranting 
Tagcloud (Intersection) ?