CLCF1

Gene Name		cardiotrophin-like cytokine factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Vesicular Exosome CRLF-CLCF1 Complex CNTFR-CLCF1 Complex
	Molecular Function	Receptor Binding Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Protein Binding Growth Factor Activity Protein Heterodimerization Activity
	Biological Process	Positive Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway JAK-STAT Cascade Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of B Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Isotype Switching To IgE Isotypes Positive Regulation Of Astrocyte Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CNTFR CRLF1
Entrez ID		23529
HPRD ID		09643
Ensembl ID		ENSG00000175505
Uniprot IDs		Q9UBD9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Death Regulation Of Neuron Apoptotic Process Regulation Of Neuron Death Negative Regulation Of Motor Neuron Apoptotic Process Ciliary Neurotrophic Factor-mediated Signaling Pathway Brainstem Development Positive Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Suckling Behavior Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Apoptotic Process Regulation Of Cell Proliferation Regulation Of Cell Death Positive Regulation Of JAK-STAT Cascade Regulation Of JAK-STAT Cascade Feeding Behavior Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Skeletal Muscle Organ Development Positive Regulation Of Peptidyl-tyrosine Phosphorylation Kidney Epithelium Development Organ Development
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