ARC

Description		activity regulated cytoskeleton associated protein
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GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Cell Projection Neuronal Cell Body Dendritic Spine Membrane Raft Synapse Postsynaptic Membrane Neuronal Ribonucleoprotein Granule Glutamatergic Synapse Virus-like Capsid Extracellular Vesicle
	Molecular Function	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Endocytosis Cytoskeleton Organization Endoderm Development Long-term Memory Anterior/posterior Pattern Specification Cell Migration Regulation Of Cell Morphogenesis Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission MRNA Transport Protein Homooligomerization Long-term Synaptic Potentiation Dendritic Spine Morphogenesis Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Intercellular Transport Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Synaptic Depression
Pathways		NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Automobile speeding propensity ( 30643258)
Interacting Genes		7 interacting genes: CSRP2 KRT15 S100P SH2D4A SPTBN4 TBX18 UBE3A
Entrez ID		23237
HPRD ID		12469
Ensembl ID		ENSG00000198576
Uniprot IDs		Q7LC44
PDB IDs		6TN7 6TNQ 6TQ0 6YTU 7R1Z 7R23 8QF4 8QF5
Enriched GO Terms of Interacting Partners?		Sperm Entry Positive Regulation Of Golgi Lumen Acidification Sinoatrial Node Cell Fate Commitment Phosphatase Binding Muscle Tissue Development Tissue Development Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Cellular PH Reduction Regulation Of Golgi Lumen Acidification Ureter Development RNA Polymerase II Transcription Repressor Complex Sinoatrial Node Cell Development Neural Plate Pattern Specification Sinoatrial Node Development Cardiac Muscle Cell Fate Commitment Regulation Of SA Node Cell Action Potential Neural Plate Anterior/posterior Regionalization Cytoskeletal Protein-membrane Anchor Activity Clustering Of Voltage-gated Sodium Channels Axon Hillock Cell Body Fiber Paranode Region Of Axon Spectrin
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