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RPS20 and TNFAIP3
Number of citations of the paper that reports this interaction (PubMedID
34839354
)
50
Data Source:
BioGRID
(two hybrid)
RPS20
TNFAIP3
Description
ribosomal protein S20
TNF alpha induced protein 3
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Ribosome
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Synapse
Extracellular Exosome
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Lysosome
Cytosol
Extracellular Exosome
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
MDM2/MDM4 Family Protein Binding
Ubiquitin Ligase Inhibitor Activity
Protease Binding
DNA Binding
Catalytic Activity
Ubiquitin-protein Transferase Activity
Cysteine-type Deubiquitinase Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Zinc Ion Binding
Transferase Activity
Hydrolase Activity
Enzyme Binding
Kinase Binding
Identical Protein Binding
Ubiquitin Binding
Metal Ion Binding
K63-linked Deubiquitinase Activity
K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
Cytoplasmic Translation
Translation
Positive Regulation Of Signal Transduction By P53 Class Mediator
B-1 B Cell Homeostasis
Response To Molecule Of Bacterial Origin
Immune System Process
Regulation Of Germinal Center Formation
Negative Regulation Of Chronic Inflammatory Response
Proteolysis
Apoptotic Process
Inflammatory Response
Cytoskeleton Organization
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Cell Migration
Protein Deubiquitination
Positive Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Ubiquitination
Response To Muramyl Dipeptide
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Toll-like Receptor 5 Signaling Pathway
Protein K11-linked Deubiquitination
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Bone Resorption
Negative Regulation Of Innate Immune Response
Negative Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Defense Response To Virus By Host
Negative Regulation Of Inflammatory Response
Negative Regulation Of B Cell Activation
Regulation Of Vascular Wound Healing
Cellular Response To Hydrogen Peroxide
Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Protein K63-linked Deubiquitination
Protein K48-linked Ubiquitination
Protein K48-linked Deubiquitination
Cellular Response To Lipopolysaccharide
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Tolerance Induction To Lipopolysaccharide
Establishment Of Protein Localization To Vacuole
Negative Regulation Of Osteoclast Proliferation
Cellular Response To Oxygen-containing Compound
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Hepatocyte Proliferation
Negative Regulation Of CD40 Signaling Pathway
Negative Regulation Of Endothelial Cell Apoptotic Process
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
NOD1/2 Signaling Pathway
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NF-kappa-B signaling pathway
Ovarian tumor domain proteases
Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS
Height (
18391951
)
Refractive error (
32231278
)
Systemic lupus erythematosus (
28714469
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
32296059
)
Autoimmune traits (pleiotropy) (
30572963
)
Cardiac Troponin-T levels (
23247143
)
Celiac disease (
20190752
22057235
)
Celiac disease and Rheumatoid arthritis (
26546613
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Cutaneous psoriasis (
26626624
)
Hodgkin's lymphoma (
30194254
)
Inflammatory bowel disease (
23128233
)
Inflammatory skin disease (
25574825
)
Malaria (
31844061
)
Multiple sclerosis (
24076602
)
Phosphatidylcholine-ether levels (
31551469
)
Primary biliary cholangitis (
26394269
)
Psoriasis (
25574825
19169254
25903422
20953190
23143594
)
Psoriasis vulgaris (
26626624
)
Rheumatoid arthritis (
24449572
24390342
23143596
20453841
32723749
30423114
17982456
)
Rheumatoid arthritis (ACPA-positive) (
24532676
23143596
)
Sjögren's syndrome (
24097066
24097067
)
Systemic lupus erythematosus (
19165918
28714469
27399966
26663301
26502338
23273568
19838195
19838193
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Systemic lupus erythematosus or rheumatoid arthritis (
27193031
)
Systemic sclerosis (
28314753
)
Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) (
30573655
)
Tonsillectomy (
28928442
27182965
)
Type 1 diabetes (
34127860
)
Interacting Genes
26 interacting genes:
APP
BARD1
CREBBP
DUX4
ECT2
FOXP1
HMGB1
IL7R
MPHOSPH6
NDRG1
NRAS
PALS2
PAXIP1
PDE4B
PIK3CA
PLEKHO1
PTEN
RABAC1
REEP6
RNF10
SP3
SUN2
TNFAIP3
TRAF6
USP40
ZNF598
61 interacting genes:
ANKRD13D
ARRDC3
ATP2A2
CALCOCO2
CCDC50
CCDC90B
CHUK
CLEC4G
COL1A1
DRC4
FABP4
GIT2
GNAI2
IKBKB
IKBKG
LAPTM5
LNX1
MAP3K5
OCLN
PCBP1
PFKL
PIBF1
PSMA7
RAD23A
RBCK1
RIPK1
RLIM
RNF11
RNF14
RNF168
RNF216
RNF5
RPS15
RPS20
SNAI1
TAX1BP1
TICAM1
TIFA
TNIP1
TNIP2
TRAF1
TRAF2
TRAF6
TRIM2
TRIM23
TRIM3
TRIM5
TRIM8
UBC
UBE2D1
UBE2N
UBQLN1
UBXN6
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZFAND5
ZNF251
Entrez ID
6224
7128
HPRD ID
04728
01857
Ensembl ID
ENSG00000008988
ENSG00000118503
Uniprot IDs
P60866
P21580
PDB IDs
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7QP6
7QP7
7R4X
7TQL
7XNX
7XNY
8G5Y
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
2EQE
2EQF
2EQG
2VFJ
3DKB
3OJ3
3OJ4
3VUW
3VUX
3VUY
3ZJD
3ZJE
3ZJF
3ZJG
5LRX
5V3B
5V3P
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Immune System Process
Regulation Of Immune Response
Myeloid Leukocyte Activation
Leukocyte Activation
Cell Activation
Regulation Of Cell Population Proliferation
Positive Regulation Of Immune Response
Multicellular Organismal-level Homeostasis
Immune System Process
Regulation Of Interleukin-1 Beta Production
Cellular Response To Stress
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Positive Regulation Of Macromolecule Metabolic Process
DNA Damage Response
Regulation Of Adaptive Immune Response
Regulation Of Interleukin-1 Production
DNA Recombination
Regulation Of Apoptotic Process
Activation Of Immune Response
Myeloid Progenitor Cell Differentiation
Intracellular Signal Transduction
Regulation Of Programmed Cell Death
Response To Radiation
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Metabolic Process
Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Interleukin-6 Production
Positive Regulation Of Transcription By RNA Polymerase II
T Cell Differentiation
Regulation Of Immune System Process
Cell Activation Involved In Immune Response
Response To Lipopolysaccharide
Positive Regulation Of Signal Transduction
Macrophage Activation
RAGE Receptor Binding
Regulation Of Tumor Necrosis Factor Production
Response To Stress
Damaged DNA Binding
Mononuclear Cell Differentiation
Response To Molecule Of Bacterial Origin
Regulation Of Interleukin-12 Production
Cellular Response To Lipopolysaccharide
Regulation Of Interleukin-2 Production
Hemopoiesis
Regulation Of Developmental Process
Nucleus
Immune Response-activating Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Cellular Response To Molecule Of Bacterial Origin
Protein Ubiquitination
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Canonical NF-kappaB Signal Transduction
Post-translational Protein Modification
Ubiquitin Protein Ligase Activity
Regulation Of Intracellular Signal Transduction
Ubiquitin-protein Transferase Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Modification-dependent Protein Catabolic Process
Regulation Of Cell Communication
Regulation Of Signaling
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Proteolysis Involved In Protein Catabolic Process
Regulation Of Signal Transduction
Positive Regulation Of DNA-binding Transcription Factor Activity
Ubiquitin-dependent Protein Catabolic Process
Cytoplasm
Positive Regulation Of Intracellular Signal Transduction
Macromolecule Catabolic Process
Regulation Of Immune Response
Protein Modification Process
Cytosol
Activation Of Innate Immune Response
Activation Of Immune Response
Protein K63-linked Ubiquitination
Immune Response-activating Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Signaling Adaptor Activity
Protein Metabolic Process
Positive Regulation Of Signal Transduction
Identical Protein Binding
Catabolic Process
Innate Immune Response-activating Signaling Pathway
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Immune Response
Positive Regulation Of Metabolic Process
Tumor Necrosis Factor-mediated Signaling Pathway
Immune Response-regulating Signaling Pathway
Protein Catabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Innate Immune Response
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Defense Response
Protein Sequestering Activity
Positive Regulation Of Innate Immune Response
Positive Regulation Of Immune System Process
Proteasomal Protein Catabolic Process
Cell Surface Toll-like Receptor Signaling Pathway
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Tagcloud (Intersection)
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